Description

(S)-5-Methoxy-2,3-Dihydro-1H-Inden-1-Amine CAS NO 132154-15-5 is a chiral amine derivative of the indane scaffold, serving as a critical chiral building block and intermediate in advanced organic synthesis. Its enantiopure (S)-configuration is essential for imparting specific biological activity in pharmaceutical development. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the discovery and synthesis of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and cardiovascular targets.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel therapeutic agents.
• Asymmetric Synthesis: Used as a chiral auxiliary or precursor in catalytic asymmetric reactions to construct complex molecules.
• Medicinal Chemistry Research: Serves as a core scaffold for structure-activity relationship (SAR) studies in drug discovery programs.
• API Development: An intermediate in the synthetic route of potential drug candidates targeting neurological and cardiovascular diseases.
• Chemical Reference Standard: Employed as a high-purity standard for analytical method development and quality control in pharmaceutical manufacturing.
• Academic Research: Utilized in university and institutional labs for studying chiral induction and novel synthetic methodologies.

Basic Information

Product Name	(S)-5-Methoxy-2,3-Dihydro-1H-Inden-1-Amine
CAS No.	132154-15-5
Molecular Formula	C10H13NO
Molecular Weight	163.22 g/mol
Synonyms	(1S)-5-Methoxy-2,3-dihydro-1H-inden-1-amine; (S)-5-Methoxyindan-1-amine; (S)-1-Amino-5-methoxyindane; (S)-5-Methoxy-1-indanamine; (S)-5-Methoxy-2,3-dihydro-1H-inden-1-amine; (S)-5-Methoxyindanamine; 5-Methoxy-(1S)-indan-1-amine; 132154-15-5
EINECS	Contact for details

Quality Control

Our (S)-5-Methoxy-2,3-Dihydro-1H-Inden-1-Amine is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) detailing identity, purity, and chiral excess are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.