Description

1,4-Dioxaspiro[2.2]Pentane,2,5-Bis(1-Methylethyl)-,[2Alpha,3Alpha(S*)]-(9Ci) is a specialized spirocyclic acetal compound, identified by CAS NO 131864-23-8, valued for its unique stereochemistry and functional group. This compound serves as a crucial advanced intermediate in the synthesis of complex organic molecules, particularly in the pharmaceutical and agrochemical sectors. It is primarily sought by R&D chemists and process development scientists for constructing chiral frameworks and protecting sensitive functional groups during multi-step syntheses.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of active pharmaceutical ingredients (APIs), especially those requiring specific stereocenters.
• Agrochemical Synthesis: Used in the research and development of novel pesticides and herbicides where its spirocyclic structure imparts specific biological activity.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances that require high-purity, complex intermediates.
• Academic & Industrial Research: A valuable reagent in methodological chemistry research for developing new synthetic routes and catalytic processes.
• Material Science: Potential monomer or precursor for synthesizing specialized polymers with unique thermal or mechanical properties.

Basic Information

Product Name	1,4-Dioxaspiro[2.2]Pentane,2,5-Bis(1-Methylethyl)-,[2Alpha,3Alpha(S*)]-(9Ci)
CAS No.	131864-23-8
Molecular Formula	C11H20O2
Molecular Weight	184.28 g/mol
Synonyms	2,5-Diisopropyl-1,4-dioxaspiro[2.2]pentane; (2α,3α)-2,5-Bis(1-methylethyl)-1,4-dioxaspiro[2.2]pentane; Spiro[2.2]pentane-1,4-dione, 2,5-diisopropyl-, cyclic acetal; 2,5-Diisopropyl-1,4-dioxaspiropentane; Chiral spiroacetal diisopropyl derivative; 131864-23-8; (2S*,3S*)-2,5-Diisopropyl-1,4-dioxaspiro[2.2]pentane
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality protocols to ensure batch-to-batch consistency and high chemical purity. Quality is verified through comprehensive analytical techniques including HPLC, GC, and chiral analysis. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting purity, enantiomeric excess (where applicable), and impurity profiles. We support cGMP standards for pharmaceutical applications and can tailor specifications to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be sensitive to prolonged exposure to moisture and air. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.