Description

(1-Naphthylaminomethylene)Malonic Acid Diethyl Ester is a specialized organic building block and chemical intermediate of significant interest in advanced synthesis. Its core value lies in its bifunctional structure, which incorporates both a reactive naphthylamine moiety and a malonate ester group, making it a versatile precursor for constructing complex heterocyclic and polycyclic frameworks. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of naphthalene-based drug candidates, including potential kinase inhibitors and anti-inflammatory agents.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and plant growth regulators.
• Organic Light-Emitting Diode (OLED) Materials: Serves as a precursor for electron-transport or host materials in OLED device fabrication due to the naphthalene core.
• Dye and Pigment Intermediate: Employed in the synthesis of advanced organic dyes and colorants with specific light-absorption properties.
• Ligand Synthesis for Catalysis: Useful for preparing complex nitrogen-containing ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Academic and Contract Research: A valuable reagent for methodological studies in organic chemistry, particularly in cyclization and condensation reactions.

Basic Information

Product Name	(1-Naphthylaminomethylene)Malonic Acid Diethyl Ester
CAS No.	131775-94-5
Molecular Formula	C₁₈H₂₁NO₄
Molecular Weight	315.36 g/mol
Synonyms	Diethyl (1-Naphthylaminomethylene)malonate; Diethyl [(1-Naphthylamino)methylene]malonate; Malonic acid, (1-naphthylaminomethylene)-, diethyl ester; 2-[(1-Naphthylamino)methylene]malonic acid diethyl ester; 1-Naphthylaminomethylenemalonic acid diethyl ester; (1-Naphthylaminomethylene)propanedioic acid diethyl ester; N-[(1-Naphthylamino)methylene]malonic acid diethyl ester
EINECS	Contact for details

Quality Control

Our (1-Naphthylaminomethylene)Malonic Acid Diethyl Ester is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and GC for residual solvent analysis, to ensure it meets the high standards required for research and industrial synthesis. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be light-sensitive and should be handled under an inert atmosphere for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Standard Grade)
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.