Description

3-(Hydroxymethyl)-2-Pyridinecarbonitrile is a versatile pyridine derivative that serves as a critical building block in advanced organic synthesis. Its bifunctional structure, featuring both a hydroxymethyl and a nitrile group, makes it a valuable precursor for constructing complex heterocyclic systems and active pharmaceutical ingredients (APIs). This compound is primarily sought by research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel compounds and fine-tuning molecular properties.

Application

• Pharmaceutical Intermediate: Key synthon for the development of novel drug candidates, particularly in kinase inhibitor and central nervous system (CNS) active compound research.
• Agrochemical Synthesis: Used as a precursor in the manufacture of advanced pesticides and herbicides, leveraging the pyridine core for bioactivity.
• Ligand and Catalyst Development: Serves as a starting material for synthesizing specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of functionalized polymers and organic electronic materials due to its modifiable functional groups.
• Chemical Biology Probes: Utilized to create tagged molecules and probes for studying biological pathways and enzyme functions.
• Custom Synthesis and Contract Manufacturing: A fundamental building block for custom chemical synthesis services catering to R&D and pilot-scale production.

Basic Information

Product Name	3-(Hydroxymethyl)-2-Pyridinecarbonitrile
CAS No.	131747-56-3
Molecular Formula	C7H6N2O
Molecular Weight	134.14 g/mol
Synonyms	2-Cyano-3-pyridinemethanol; 3-Pyridinemethanol, 2-cyano-; (2-Cyanopyridin-3-yl)methanol; 2-Cyanonicotinyl alcohol; 3-Hydroxymethyl-2-cyanopyridine; 2-Cyano-3-hydroxymethylpyridine; Nicotinonitrile, 3-(hydroxymethyl)-
EINECS	Contact for details

Quality Control

Our 3-(Hydroxymethyl)-2-Pyridinecarbonitrile is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) with batch-specific data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after use to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.