Description

1H-Indazole-3-Acetic Acid, Methyl Ester is a versatile indazole derivative, a key heterocyclic building block in advanced organic synthesis. This compound matters for its role as a crucial intermediate in the development of pharmaceuticals and agrochemicals, enabling the construction of complex molecular architectures. It is primarily needed by research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting inflammation, central nervous system (CNS) disorders, and oncology.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides, herbicides, and plant growth regulators.
• Fine Chemical Building Block: Serves as a versatile scaffold for constructing complex heterocyclic compounds in custom synthesis and material science research.
• Biochemical Research: Employed as a standard or reagent in enzymatic studies and biochemical pathway investigations.
• Academic & Industrial R&D: Utilized in medicinal chemistry programs for structure-activity relationship (SAR) studies and lead optimization.

Basic Information

Product Name	1H-Indazole-3-Acetic Acid, Methyl Ester
CAS No.	131666-74-5
Molecular Formula	C10H10N2O2
Molecular Weight	190.20 g/mol
Synonyms	Methyl 1H-Indazole-3-acetate; Methyl (1H-Indazol-3-yl)acetate; 3-(Methoxycarbonylmethyl)-1H-indazole; 1H-Indazole-3-acetic acid methyl ester; Indazole-3-acetic Acid Methyl Ester; 3-Carboxymethylindazole Methyl Ester; (1H-Indazol-3-yl)acetic acid methyl ester
EINECS	Contact for details

Quality Control

Our 1H-Indazole-3-Acetic Acid, Methyl Ester is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed chromatographic data (HPLC/GC) are provided and available upon request, supporting compliance with cGMP and ISO 9001 standards for research and commercial use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.