Description

Methyl 2-(3-(Trifluoromethyl)Benzamido)Acetate CAS NO 131648-66-3 is a high-value trifluoromethylated benzamide derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its core value lies in providing a versatile molecular scaffold for constructing complex pharmacophores and functional materials. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and specialty chemical industries who require high-purity building blocks for drug discovery and material science applications.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in the development of compounds targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Research: Used in the creation of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Ligand & Catalyst Development: Serves as a precursor for designing specialized ligands in asymmetric catalysis and organometallic chemistry.
• Material Science Precursor: Employed in the synthesis of monomers and polymers with specific optical or electronic properties for advanced materials.
• Chemical Biology Probe Synthesis: Utilized to create molecular probes for studying enzyme function and protein-protein interactions in biological systems.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	Methyl 2-(3-(Trifluoromethyl)Benzamido)Acetate
CAS No.	131648-66-3
Molecular Formula	C11H10F3NO3
Molecular Weight	261.20 g/mol
Synonyms	Methyl N-[2-oxo-2-(3-(trifluoromethyl)phenyl)ethyl]carbamate; Glycine, N-[3-(trifluoromethyl)benzoyl]-, methyl ester; Methyl (3-(trifluoromethyl)benzamido)acetate; 2-[(3-Trifluoromethylbenzoyl)amino]acetic acid methyl ester; m-Trifluoromethylhippuric acid methyl ester; Methyl α-[(3-trifluoromethylbenzoyl)amino]acetate; N-(Methoxycarbonylmethyl)-3-(trifluoromethyl)benzamide
EINECS	Contact for details

Quality Control

Our Methyl 2-(3-(Trifluoromethyl)Benzamido)Acetate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical documentation, including Certificates of Analysis (COA) with detailed HPLC/GC profiles, to support your regulatory and R&D requirements. Our quality commitment aligns with cGMP principles for advanced intermediates, ensuring reliability for critical synthesis steps.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Any single unknown impurity	≤0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.