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3-(4-Azidobenzoyl)-6-Hydroxy-2-(4-Hydroxyphenyl)Benzo(B)Thiophene CAS NO 131589-60-1


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CAS No.:131589-60-1

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

3-(4-Azidobenzoyl)-6-Hydroxy-2-(4-Hydroxyphenyl)Benzo(B)Thiophene is a specialized organic compound featuring a benzothiophene core functionalized with azido and phenolic groups. This unique structure makes it a valuable photoaffinity labeling agent and a versatile building block for advanced materials and pharmaceutical research. It is primarily utilized by research scientists and process chemists in the fields of medicinal chemistry, chemical biology, and materials science for developing novel probes and functional polymers.

Application

  • Photoaffinity Labeling Probes: Acts as a key intermediate in synthesizing probes for studying protein-ligand interactions and biological target identification.
  • Medicinal Chemistry Research: Serves as a sophisticated scaffold for the design and synthesis of novel drug candidates, particularly in oncology and CNS disorders.
  • Polymer & Materials Science: Used as a functional monomer or cross-linker in the development of photosensitive polymers, hydrogels, and advanced coatings.
  • Bioconjugation Chemistry: The azido group enables efficient "click chemistry" reactions (e.g., CuAAC) for attaching fluorescent tags or other functional moieties to biomolecules.
  • Chemical Biology Tool Development: Integral for creating activity-based probes (ABPs) to visualize enzyme activity and function within complex biological systems.
  • Academic & Industrial R&D: Supports fundamental and applied research in universities, government labs, and biotechnology/pharmaceutical companies.

Basic Information

Item Detail
Product Name 3-(4-Azidobenzoyl)-6-Hydroxy-2-(4-Hydroxyphenyl)Benzo(B)Thiophene
CAS No. 131589-60-1
Molecular Formula C21H13N3O3S
Molecular Weight 387.41 g/mol
Synonyms 3-(4-Azidobenzoyl)-6-hydroxy-2-(4-hydroxyphenyl)benzothiophene; 6-Hydroxy-2-(4-hydroxyphenyl)-3-(4-azidobenzoyl)benzo[b]thiophene; 3-(p-Azidobenzoyl)-6-hydroxy-2-(p-hydroxyphenyl)benzothiophene; Azidobenzoyl Hydroxyphenyl Benzothiophene Derivative; Photoaffinity Benzothiophene Intermediate; CAS 131589-60-1
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Quality Control

Our production of 3-(4-Azidobenzoyl)-6-Hydroxy-2-(4-Hydroxyphenyl)Benzo(B)Thiophene adheres to stringent quality protocols to ensure batch-to-batch consistency and reliability for sensitive research applications. Each lot is characterized using advanced analytical techniques including HPLC, NMR, and MS to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to the light-sensitive nature of the azido functional group, prolonged exposure to light should be avoided. Keep the container tightly sealed in a dry environment to maintain stability.

Specification

Item Specification
Appearance Yellow to light brown powder
Identification (IR) Conforms to structure
Identification (HPLC) Conforms to reference
Purity (HPLC) ≥ 95.0%
Water Content (KF) ≤ 1.0%
Residue on Ignition ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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