Description

Ethyl 2-(4-Amino-6-Fluorochroman-4-Yl)Acetate is a high-purity, fluorinated chroman derivative that serves as a critical advanced pharmaceutical intermediate. Its value lies in its unique molecular scaffold, which is essential for synthesizing novel bioactive compounds targeting central nervous system and cardiovascular disorders. This product is primarily needed by research institutions and pharmaceutical manufacturers engaged in the development of new chemical entities and active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel fluorinated drug candidates.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new therapeutic agents.
• Active Pharmaceutical Ingredient (API) Development: Serves as a precursor in the multi-step synthesis of complex target molecules.
• Chemical Reference Standard: Employed as a high-purity standard for analytical method development and validation in QC laboratories.
• Organic Synthesis: Utilized in academic and industrial R&D for constructing chroman-based heterocyclic compounds.

Basic Information

Product Name	Ethyl 2-(4-Amino-6-Fluorochroman-4-Yl)Acetate
CAS No.	131436-64-1
Molecular Formula	C₁₃H₁₆FNO₃
Molecular Weight	253.27 g/mol
Synonyms	Ethyl (4-Amino-6-fluoro-4H-chromen-4-yl)acetate; 4H-1-Benzopyran-4-acetic acid, 4-amino-6-fluoro-, ethyl ester; 4-Amino-6-fluorochroman-4-acetic acid ethyl ester; 6-Fluoro-4-aminotetrahydrochromanylacetic acid ethyl ester; Ethyl 4-Amino-6-fluorochroman-4-ylacetate; 131436-64-1; 4-Amino-6-fluorochroman-4-ylacetic acid ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl 2-(4-Amino-6-Fluorochroman-4-Yl)Acetate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical research and development. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). This compound is light-sensitive (store away from light) and hygroscopic (moisture-sensitive); therefore, containers should be kept sealed under an inert atmosphere when not in use to prevent degradation and moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.