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(R)-3-Azido-1,2-Propanediol CAS NO 131321-84-1


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CAS No.:131321-84-1

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

(R)-3-Azido-1,2-Propanediol is a chiral building block of significant value in synthetic organic chemistry, particularly for the preparation of complex bioactive molecules. Its core value lies in the versatile azido functional group, which serves as a key precursor for "click chemistry" reactions, enabling efficient and selective conjugation. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require high-purity, enantiomerically pure intermediates for drug discovery and development.

Application

  • Pharmaceutical Intermediate: A key chiral synthon for the synthesis of nucleoside analogs, antiviral agents, and other active pharmaceutical ingredients (APIs).
  • Click Chemistry Reagent: The azido group readily participates in copper-catalyzed azide-alkyne cycloaddition (CuAAC) for bioconjugation, polymer modification, and material surface functionalization.
  • Glycochemistry Building Block: Used in the stereoselective synthesis of complex carbohydrates, glycopeptides, and glycolipids for biological studies.
  • Agrochemical Synthesis: Serves as an intermediate in the development of novel, chiral pesticides and herbicides.
  • Ligand and Catalyst Development: Employed in the creation of chiral ligands for asymmetric catalysis.
  • Polymer Science: Acts as a monomer or cross-linking agent for the production of functionalized polymers with tailored properties.

Basic Information

Product Name (R)-3-Azido-1,2-Propanediol
CAS No. 131321-84-1
Molecular Formula C3H7N3O2
Molecular Weight 117.11 g/mol
Synonyms (R)-3-Azido-1,2-dihydroxypropane; (R)-Azidoglycerol; (R)-3-Azidopropane-1,2-diol; (R)-1,2-Dihydroxy-3-azidopropane; (R)-Glycidyl Azide Diol; (R)-O-(2,3-Dihydroxypropyl)hydroxylamine; (R)-AzdG
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Quality Control

Our (R)-3-Azido-1,2-Propanediol is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure compliance with high-purity standards for research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and enantiomeric excess is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C) under an inert atmosphere (e.g., nitrogen or argon) to prevent oxidation. Keep away from heat, sparks, and open flame.

Specification

Item Specification
Appearance Colorless to pale yellow liquid
Identification (IR) Conforms to structure
Purity (HPLC) ≥ 97.0%
Enantiomeric Excess (Chiral HPLC) ≥ 98.0%
Water Content (KF) ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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