Description

n-(4-Azido-2,3,5,6-Tetrafluorobenzoyl)Tyrosine is a specialized, high-purity biochemical building block designed for advanced research and synthesis. This compound is critical for applications requiring precise photoaffinity labeling and cross-linking due to its reactive azido and tetrafluorobenzoyl functional groups. It is primarily utilized by researchers and process developers in the pharmaceutical, biotechnology, and chemical synthesis industries for developing novel probes, bioconjugates, and active pharmaceutical ingredients (APIs).

Application

• Photoaffinity Labeling Probes: Acts as a key intermediate for synthesizing probes to study protein-ligand interactions and biological target identification.
• Bioconjugation and Cross-linking: Used in the development of antibody-drug conjugates (ADCs) and other bioconjugates for targeted drug delivery.
• Chemical Biology Research: Serves as a versatile tool for modifying peptides and proteins to investigate structure-activity relationships (SAR).
• Pharmaceutical Intermediate: Employed in the synthesis of complex molecules and potential active pharmaceutical ingredients (APIs) with specific targeting moieties.
• Material Science: Can be utilized in surface functionalization and the creation of advanced polymeric materials with specific biological activity.
• Proteomics and Genomics: Facilitates the study of biomolecular interactions and pathways through targeted labeling strategies.

Basic Information

Product Name	n-(4-Azido-2,3,5,6-Tetrafluorobenzoyl)Tyrosine
CAS No.	131238-01-2
Molecular Formula	C₁₆H₈F₄N₄O₄
Molecular Weight	396.26 g/mol
Synonyms	N-[4-Azido-2,3,5,6-tetrafluorobenzoyl]tyrosine; 4-Azido-2,3,5,6-tetrafluorobenzoic Acid Tyrosine Amide; Tyrosine, N-(4-azido-2,3,5,6-tetrafluorobenzoyl)-; 131238-01-2; 4-Azido-tetrafluorobenzoyl-tyrosine; ATFB-Tyr; Photoaffinity Tyrosine Derivative; Tetrafluoroazidobenzoyl Tyrosine
EINECS	Contact for details

Quality Control

Our n-(4-Azido-2,3,5,6-Tetrafluorobenzoyl)Tyrosine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (refrigerated) or as indicated on the label or COA. This material is strictly light-sensitive and hygroscopic; it must be handled under inert atmosphere or dry conditions when appropriate to maintain stability and prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Assay	≥ 97%
Water Content	≤ 1.0%
Residual Solvents	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.