Description

Ethyl 3-(tert-Butoxycarbonylamino)-3-Methylbutanoate is a high-purity, protected amino acid ester derivative, serving as a critical building block in advanced organic synthesis. Its primary value lies in its role as a versatile intermediate for constructing complex molecules, particularly in pharmaceutical research and development. This compound is essential for medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries who require reliable, high-quality intermediates for peptide mimetics and active pharmaceutical ingredient (API) synthesis.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in the development of protease inhibitors and other bioactive peptides.
• Peptidomimetic Synthesis: Used to introduce sterically hindered, protected amino acid motifs into peptide chains to enhance metabolic stability and bioavailability.
• Agrochemical Research: Intermediate in the development of new pesticides and herbicides that utilize amino acid-based active ingredients.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing specialized compounds for clients.
• Academic & R&D Laboratories: Employed in university and institutional research for methodological studies in organic chemistry and medicinal chemistry.
• Protecting Group Chemistry: Serves as a practical example and reagent in studies involving the introduction and removal of the tert-butoxycarbonyl (Boc) protecting group.

Basic Information

Product Name	Ethyl 3-(tert-Butoxycarbonylamino)-3-Methylbutanoate
CAS No.	130985-42-1
Molecular Formula	C13H25NO4
Molecular Weight	259.34 g/mol
Synonyms	Ethyl 3-[(tert-Butoxycarbonyl)amino]-3-methylbutanoate; 3-[(tert-Butoxycarbonyl)amino]-3-methylbutanoic Acid Ethyl Ester; Ethyl 3-(Boc-amino)-3-methylbutyrate; Boc-β-aminoisobutyric Acid Ethyl Ester; β-(Boc-amino)-isobutyric Acid Ethyl Ester; BOC-AIB-OEt; 3-Methyl-3-[(2-methylpropan-2-yl)oxycarbonylamino]butanoic acid ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl 3-(tert-Butoxycarbonylamino)-3-Methylbutanoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistent performance as a synthesis intermediate. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong acids and incompatible materials such as strong oxidizing agents. The container must be kept tightly closed to prevent moisture absorption.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.