Description

Azidotris(Diethylamino)Phosphonium Bromide is a specialized organophosphorus compound featuring a reactive azide group. This unique structure makes it a valuable reagent for the synthesis of complex molecules, particularly in the field of pharmaceutical research and advanced material science. It is primarily sought after by R&D chemists and process development scientists working on click chemistry, bioconjugation, and the development of novel active pharmaceutical ingredients (APIs).

Application

• Click Chemistry Reagent: A key precursor for Staudinger-Bertozzi ligation, enabling the efficient and selective formation of amide bonds under mild conditions for bioconjugation.
• Pharmaceutical Intermediate: Used in the synthesis of complex drug candidates, particularly those requiring the introduction of phosphonium or azide functionalities.
• Polymer Modification: Facilitates the functionalization of polymer backbones to introduce specific chemical handles or alter material properties.
• Peptide and Protein Labeling: Enables site-specific tagging of biomolecules for imaging, diagnostic, or therapeutic purposes.
• Material Science Research: Employed in the development of novel surfaces, coatings, and nanomaterials with tailored reactivity.
• Chemical Biology Probes: Serves as a building block for creating activity-based probes to study enzyme function and metabolic pathways.

Basic Information

Product Name	Azidotris(Diethylamino)Phosphonium Bromide
CAS No.	130888-29-8
Molecular Formula	C12H30BrN6P
Molecular Weight	369.28 g/mol
Synonyms	Azidotris(diethylamino)phosphonium Bromide; (Diethylamino)(azido)phosphonium Bromide; Phosphonium, azidotris(diethylamino)-, bromide; Tris(diethylamino)azidophosphonium Bromide; Azido-tris-(diethylamino)-phosphonium Bromide
EINECS	Contact for details

Quality Control

Our Azidotris(Diethylamino)Phosphonium Bromide is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, essential for sensitive synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality system is designed to meet the rigorous standards demanded by research and development laboratories.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is easily oxidized and should be handled and stored under an inert atmosphere (e.g., nitrogen or argon) to maintain stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.