Description

1,2-Phenylenebis(Ethane-2,1-Diyl) Dimethanesulfonate is a specialized organic synthetic intermediate, specifically a dimethanesulfonate ester derivative of a phenylenediethanolic structure. This compound matters for its role as a key building block in the synthesis of complex molecules, particularly in pharmaceutical research and fine chemical manufacturing. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced material sectors for constructing molecular scaffolds and introducing functional groups.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for candidates targeting central nervous system (CNS) disorders or as a linker in prodrug development.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and plant growth regulators where its bifunctional leaving group capability is valuable.
• Polymer Chemistry: Serves as a cross-linking agent or monomer in the development of specialty polymers, resins, and high-performance materials with specific thermal or mechanical properties.
• Ligand and Catalyst Preparation: Employed in organometallic chemistry for the synthesis of complex ligands and catalysts used in asymmetric synthesis and coupling reactions.
• Chemical Research & Development: A versatile tool in academic and industrial labs for exploring new organic reactions, particularly nucleophilic substitution and cyclization reactions.
• Material Science: Investigated for use in the creation of organic electronic materials, such as components for OLEDs or conductive polymers.

Basic Information

Product Name	1,2-Phenylenebis(Ethane-2,1-Diyl) Dimethanesulfonate
CAS No.	130800-04-3
Molecular Formula	C14H22O6S2
Molecular Weight	350.45 g/mol
Synonyms	1,2-Bis(2-methanesulfonyloxyethyl)benzene; Benzene-1,2-diylbis(ethane-2,1-diyl) dimethanesulfonate; o-Xylene-α,α'-diol dimethanesulfonate; 1,2-Bis(2-mesyloxyethyl)benzene; o-Phenylenediethanediyl dimethanesulfonate; Mesylate ester of o-phenylenediethanol; NSC 405124; o-Xylylene dimethanesulfonate
EINECS	Contact for details

Quality Control

Our 1,2-Phenylenebis(Ethane-2,1-Diyl) Dimethanesulfonate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and process chemistry. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are available upon request. We can support development projects with custom specifications aligned with ICH guidelines for pharmaceutical impurities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Consider storing under an inert atmosphere for long-term stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Any single impurity ≤ 0.5%; Total impurities ≤ 1.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.