Description

Chlorambucil-Arachidonic Acid Conjugate is a bifunctional chemical entity designed for targeted therapeutic and advanced research applications. This conjugate strategically links the alkylating agent chlorambucil with arachidonic acid, a key polyunsaturated fatty acid, to potentially enhance drug delivery and specificity. It is primarily utilized by pharmaceutical researchers and developers in the fields of oncology drug discovery and prodrug development, where precise targeting and controlled release mechanisms are critical.

Application

• Oncology Research & Targeted Drug Delivery: Serves as a key intermediate in the development of novel chemotherapeutic agents designed for selective action on cancer cells.
• Prodrug Synthesis: Used as a building block for creating prodrugs that leverage metabolic pathways for activation, potentially improving therapeutic index and reducing systemic toxicity.
• Biochemical & Pharmacological Studies: Employed in research to investigate the interplay between alkylating agents and lipid metabolism, and to study novel mechanisms of action.
• Pharmaceutical Intermediate: Acts as a critical synthetic precursor for the manufacture of specialized active pharmaceutical ingredients (APIs) in advanced therapeutic pipelines.
• Academic & Institutional Research: Utilized in university and institutional labs for cutting-edge studies in medicinal chemistry and molecular pharmacology.

Basic Information

Product Name	Chlorambucil-Arachidonic Acid Conjugate
CAS No.	130676-89-0
Molecular Formula	C30H43Cl2NO4
Molecular Weight	552.57 g/mol
Synonyms	4-[p-[Bis(2-chloroethyl)amino]phenyl]butyric Acid Arachidonate; Arachidonic Acid-Chlorambucil Ester; Chlorambucil Arachidonate; Arachidonoyl Chlorambucil; 5,8,11,14-Eicosatetraenoyl Chlorambucil; Leukeran-Arachidonate Conjugate; NSC-Derivative 130676-89-0
EINECS	Contact for details

Quality Control

Our Chlorambucil-Arachidonic Acid Conjugate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and development. Comprehensive Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are provided to guarantee traceability and consistency for your critical projects.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label or COA. For long-term storage, consider storing under an inert atmosphere at lower temperatures (e.g., -20°C) to maintain stability. Keep the container in a dry, well-ventilated place.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 95.0%
Assay	≥ 97.0%
Water Content	≤ 1.0%
Residual Solvents	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.