Description

(E)-(5R,7R)-8-Benzyloxy-7-Hydroxy-5-Methyl-5-Vinyl-Oct-2-Enoic Acid Ethyl Ester is a high-purity, chiral synthetic intermediate of significant importance in advanced pharmaceutical research and development. This compound is valued for its complex stereochemistry and functional groups, which make it a versatile building block for the synthesis of biologically active molecules. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel therapeutic agents, particularly in areas requiring sophisticated organic synthesis.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the multi-step synthesis of complex drug candidates and active pharmaceutical ingredients (APIs).
• Organic Synthesis Building Block: Utilized in research-scale and process chemistry for constructing molecules with specific stereocenters and olefin functionalities.
• Medicinal Chemistry Research: Serves as a critical scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Asymmetric Synthesis: Employed in reactions that require high enantioselectivity due to its defined (5R,7R) configuration.
• Process Development: Used in scaling up synthetic routes from laboratory to pilot plant scale for new chemical entities.
• Reference Standard: Acts as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	(E)-(5R,7R)-8-Benzyloxy-7-Hydroxy-5-Methyl-5-Vinyl-Oct-2-Enoic Acid Ethyl Ester
CAS No.	130675-12-6
Molecular Formula	C20H28O4
Molecular Weight	332.44 g/mol
Synonyms	Ethyl (E)-(5R,7R)-8-Benzyloxy-7-hydroxy-5-methyl-5-vinyloct-2-enoate; (5R,7R)-8-(Benzyloxy)-7-hydroxy-5-methyl-5-vinyl-2-octenoic Acid Ethyl Ester; 8-Benzyloxy-7-hydroxy-5-methyl-5-vinyl-oct-2-enoic acid ethyl ester; (E)-Ethyl 8-(benzyloxy)-7-hydroxy-5-methyl-5-vinyloct-2-enoate; SCHEMBL10827331; AKOS040759246; A812357
EINECS	Contact for details

Quality Control

Our (E)-(5R,7R)-8-Benzyloxy-7-Hydroxy-5-Methyl-5-Vinyl-Oct-2-Enoic Acid Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC and NMR, to ensure high chemical and enantiomeric purity suitable for demanding research applications. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.