Description

2-Methoxyphenylethyl Trimethylsilyl Ether is a specialized organosilicon compound used as a key protecting group and synthetic intermediate in advanced organic synthesis. Its value lies in providing a robust, silyl-based protective strategy for hydroxyl functionalities, enabling complex multi-step reactions in sensitive molecule construction. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries developing novel active ingredients and complex organic molecules. Precise control over its quality and purity is critical for ensuring reproducibility and yield in downstream synthetic processes.

Application

• Pharmaceutical Intermediate: Serves as a critical building block and protecting group reagent in the synthesis of complex drug candidates and active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the production of advanced pesticides, herbicides, and plant growth regulators where selective protection of alcohol groups is required.
• Fine Chemical Manufacturing: Employed in the multi-step synthesis of specialty chemicals, flavors, fragrances, and advanced materials.
• Academic & Industrial R&D: A valuable tool for chemists in research laboratories for method development and exploring new synthetic pathways.
• Peptide & Natural Product Synthesis: Facilitates the selective protection of hydroxyl groups during the intricate synthesis of peptides and complex natural product analogs.

Basic Information

Product Name	2-Methoxyphenylethyl Trimethylsilyl Ether
CAS No.	130436-69-0
Molecular Formula	C₁₂H₂₀O₂Si
Molecular Weight	224.37 g/mol
Synonyms	1-(2-Methoxyphenyl)ethyl Trimethylsilyl Ether; (1-(2-Methoxyphenyl)ethoxy)trimethylsilane; 2-Methoxyphenethyl Alcohol Trimethylsilyl Ether; 2-(Trimethylsilyloxy)-1-(2-methoxyphenyl)ethane; TMS Ether of 2-Methoxyphenethyl Alcohol; Trimethyl((1-(2-methoxyphenyl)ethoxy)silane; 2-Methoxybenzylcarbinyl Trimethylsilyl Ether
EINECS	Contact for details

Quality Control

Every batch of 2-Methoxyphenylethyl Trimethylsilyl Ether is manufactured and tested under strict quality management protocols to ensure high chemical purity and consistency. Our standard grade typically meets a purity specification of ≥97% (by GC or HPLC), suitable for demanding synthetic applications. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing key parameters such as assay, identity confirmation, and impurity profiles. We adhere to cGMP principles where applicable, and specifications can be customized to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and highly volatile nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.