Description

Carbamic Acid, [(3-Oxocyclobutyl)Methyl]-, 1,1-Dimethylethyl Ester (9Ci) is a specialized organic building block featuring a cyclobutanone core protected by a tert-butyl carbamate (Boc) group. This compound matters as a versatile and protected synthetic intermediate, enabling the controlled introduction of a reactive ketone functionality into complex molecular architectures. It is primarily needed by pharmaceutical and agrochemical research & development teams for constructing novel active ingredients and by fine chemical manufacturers engaged in custom synthesis projects.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides with unique modes of action.
• Peptidomimetics & PROTACs: Serves as a constrained scaffold in the design of peptide mimics and Proteolysis Targeting Chimeras (PROTACs) for targeted protein degradation.
• Material Science Research: Investigated as a monomer or cross-linking agent for developing advanced polymers with specific thermal or mechanical properties.
• Chemical Biology Probes: Utilized to create labeled or tagged molecules for studying biological pathways and enzyme functions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects requiring high-purity intermediates.

Basic Information

Product Name	Carbamic Acid, [(3-Oxocyclobutyl)Methyl]-, 1,1-Dimethylethyl Ester (9Ci)
CAS No.	130369-09-4
Molecular Formula	C11H19NO3
Molecular Weight	213.27 g/mol
Synonyms	tert-Butyl (3-oxocyclobutyl)methylcarbamate; N-Boc-3-aminomethylcyclobutanone; 1-[(tert-Butoxycarbonyl)amino]methyl-3-oxocyclobutane; (3-Oxocyclobutyl)methylcarbamic acid tert-butyl ester; Boc-AMCB; tert-Butyl N-[(3-oxocyclobutyl)methyl]carbamate; (3-Oxocyclobutyl)methylamine, N-Boc protected; 130369-09-4
EINECS	Contact for details

Quality Control

Our Carbamic Acid, [(3-Oxocyclobutyl)Methyl]-, 1,1-Dimethylethyl Ester (9Ci) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our quality commitment supports compliance with cGMP guidelines for advanced pharmaceutical intermediates, ensuring reliable supply for your most demanding synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The product is light-sensitive (store away from light) and should be kept under an inert atmosphere for long-term storage to preserve stability. Keep away from strong acids and organic solvents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.