Description

Carbamic Acid, [(3-Methylenecyclobutyl)Methyl]-, 1,1-Dimethylethyl Ester (9Ci) is a specialized organic compound featuring a carbamate protecting group linked to a methylenecyclobutyl moiety. This structure makes it a valuable protected intermediate in advanced organic synthesis, particularly for the controlled introduction of amine functionalities. It is primarily utilized by pharmaceutical and agrochemical R&D teams engaged in the development of novel active ingredients, where its unique scaffold offers strategic advantages in molecular design.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders or requiring complex cyclic amine structures.
• Agrochemical Research: Used in the development of new pesticides and herbicides, where the carbamate and cyclobutyl groups can contribute to specific biological activity.
• Organic Synthesis Reagent: Acts as a versatile precursor for introducing the [(3-methylenecyclobutyl)methyl]amine group into more complex molecules under controlled conditions.
• Peptide Mimetics & PROTACs: Employed in the construction of peptide-like compounds and Proteolysis-Targeting Chimeras (PROTACs) for targeted protein degradation research.
• Material Science Monomer: Potential use as a specialty monomer for creating polymers with unique thermal or mechanical properties derived from the strained cyclobutane ring.

Basic Information

Product Name	Carbamic Acid, [(3-Methylenecyclobutyl)Methyl]-, 1,1-Dimethylethyl Ester (9Ci)
CAS No.	130369-08-3
Molecular Formula	C11H19NO2
Molecular Weight	197.27 g/mol
Synonyms	tert-Butyl N-[(3-Methylenecyclobutyl)methyl]carbamate; Boc-((3-Methylenecyclobutyl)methyl)amine; N-Boc-3-Methylenecyclobutanemethylamine; 1,1-Dimethylethyl N-[(3-Methylenecyclobutyl)methyl]carbamate; tert-Butyl (3-Methylenecyclobutyl)methylcarbamate; (3-Methylenecyclobutyl)methylcarbamic Acid tert-Butyl Ester; BOC-Amine of 3-Methylenecyclobutanemethylamine
EINECS	Contact for details

Quality Control

Our production of Carbamic Acid, [(3-Methylenecyclobutyl)Methyl]-, 1,1-Dimethylethyl Ester adheres to stringent quality protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure consistency and meet the exacting standards required for research and process development. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider holding under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white solid or colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0% (Standard Grade)
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.