Description

(R)-(+)-Dimethyl-2-Benzyl- Succinate is a high-purity chiral building block and synthetic intermediate of significant importance in fine chemical synthesis. Its enantiomerically pure structure makes it a critical precursor for the development of active pharmaceutical ingredients (APIs) and other complex organic molecules. This compound is essential for research and production in the pharmaceutical, agrochemical, and advanced materials sectors, where precise stereochemistry is required.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of enantiomerically pure drugs, particularly in central nervous system (CNS) and cardiovascular therapeutic areas.
• Asymmetric Synthesis: Used as a starting material or resolving agent in catalytic asymmetric reactions to construct complex molecular architectures.
• Agrochemical Research: Serves as a precursor for developing chiral pesticides and herbicides with enhanced efficacy and environmental profiles.
• Ligand and Catalyst Development: Employed in the preparation of chiral ligands for transition metal catalysis.
• Flavor and Fragrance Industry: Potential intermediate for the synthesis of specific chiral aroma chemicals.
• Academic and R&D: A valuable compound for methodological studies in organic chemistry and new synthetic route exploration.

Basic Information

Product Name	(R)-(+)-Dimethyl-2-Benzyl- Succinate
CAS No.	130272-52-5
Molecular Formula	C13H16O4
Molecular Weight	236.26 g/mol
Synonyms	(R)-(+)-Dimethyl 2-benzylsuccinate; (R)-Dimethyl 2-Benzylbutanedioate; (2R)-2-Benzylbutanedioic Acid Dimethyl Ester; (+)-(R)-2-Benzylsuccinic Acid Dimethyl Ester; Dimethyl (R)-2-Benzylsuccinate; (R)-2-Benzylsuccinic Acid Dimethyl Ester; (R)-Methyl 2-(methoxycarbonyl)-3-phenylpropanoate; Benzylsuccinic Acid Dimethyl Ester, (R)-(+)-
EINECS	Contact for details

Quality Control

Our (R)-(+)-Dimethyl-2-Benzyl- Succinate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity assay and impurity profiling, to ensure it meets the stringent requirements for advanced synthetic applications. A Certificate of Analysis (COA) detailing specific results for chiral purity (typically >98% ee), chemical purity (by HPLC), and identity confirmation is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Specific Rotation [α]	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.