Description

(R)-2-(Cyclohexylmethyl)Succinic Acid-1-Methyl Ester is a high-purity chiral building block and synthetic intermediate of significant value in advanced organic synthesis. Its defined stereochemistry and functionalized structure make it a critical precursor for the development of enantiomerically pure pharmaceuticals and fine chemicals. This compound is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and metabolic disorder drug candidates.
• Asymmetric Synthesis: Serves as a starting material or intermediate in catalytic asymmetric reactions to introduce the (R)-configuration into target molecules.
• Agrochemical Research: Used in the development of chiral pesticides and herbicides where specific stereochemistry is required for biological activity.
• Ligand and Catalyst Preparation: Building block for the synthesis of novel chiral ligands, organocatalysts, and metal complexes.
• Fine Chemical Production: Intermediate in the multi-step synthesis of specialty chemicals, flavors, and fragrances requiring high enantiomeric purity.
• Academic & Industrial R&D: Valuable reference standard and tool compound for methodological development in organic and medicinal chemistry.

Basic Information

Product Name	(R)-2-(Cyclohexylmethyl)Succinic Acid-1-Methyl Ester
CAS No.	130165-88-7
Molecular Formula	C12H20O4
Molecular Weight	228.29 g/mol
Synonyms	(R)-1-Methyl 2-(cyclohexylmethyl)succinate; (R)-2-(Cyclohexylmethyl)butanedioic acid 1-methyl ester; Methyl (2R)-2-(cyclohexylmethyl)succinate; (R)-Methyl 2-(cyclohexylmethyl)succinate; (R)-2-Cyclohexylmethyl-succinic acid monomethyl ester; Succinic acid, 2-(cyclohexylmethyl)-, 1-methyl ester, (2R)-; (R)-Mono-methyl 2-(cyclohexylmethyl)succinate
EINECS	Contact for details

Quality Control

Our (R)-2-(Cyclohexylmethyl)Succinic Acid-1-Methyl Ester is manufactured under strict quality systems to ensure batch-to-batch consistency and high enantiomeric purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing key parameters such as assay, enantiomeric excess (e.e.), and impurity profile. We support cGMP compliance for advanced intermediates and can provide material suitable for pharmaceutical development under appropriate quality agreements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). The product is moisture-sensitive; keep the container tightly sealed under an inert atmosphere if necessary for long-term storage.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Enantiomeric Purity (Chiral HPLC)	≥ 98.0% e.e.
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.