Description

(R)-2-Isobutylsuccinic Acid-1-Methyl Ester is a high-purity chiral building block and intermediate of significant importance in asymmetric synthesis. Its defined stereochemistry makes it a valuable precursor for the development of active pharmaceutical ingredients (APIs), agrochemicals, and specialty fine chemicals. This compound is essential for research and production chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require enantiomerically pure intermediates for complex synthetic routes.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of enantiomerically pure drugs and bioactive molecules.
• Agrochemical Synthesis: Used in the production of chiral pesticides, herbicides, and plant growth regulators.
• Fine Chemical Production: Serves as a building block for fragrances, flavors, and other high-value specialty chemicals.
• Asymmetric Catalysis Research: Employed as a substrate or ligand precursor in the development of new catalytic methodologies.
• Material Science: Potential monomer or modifier for creating polymers with specific chiral properties.
• Academic & Industrial R&D: A critical reagent for exploratory chemistry in medicinal chemistry and process development labs.

Basic Information

Product Name	(R)-2-Isobutylsuccinic Acid-1-Methyl Ester
CAS No.	130165-76-3
Molecular Formula	C9H16O4
Molecular Weight	188.22 g/mol
Synonyms	(R)-1-Methyl 2-isobutylsuccinate; (R)-2-(2-Methylpropyl)butanedioic acid 1-methyl ester; Methyl (R)-2-isobutylsuccinate; (R)-Mono-methyl 2-isobutylsuccinate; (2R)-2-(2-Methylpropyl)butanedioic acid methyl ester; (R)-2-Isobutyl-succinic acid monomethyl ester; Succinic acid, 2-(2-methylpropyl)-, methyl ester, (2R)-
EINECS	Contact for details

Quality Control

Our (R)-2-Isobutylsuccinic Acid-1-Methyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity (assay), enantiomeric excess (ee), and impurity profiles are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0% ee
Specific Rotation [α]	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.