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3-(2-Chloroethyl)-6,7,8,9-Tetrahydro-9-Hydroxy-2-Methyl-4H-Pyrido[1,2-A]Pyrimidin-4-One CAS NO 130049-82-0


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CAS No.:130049-82-0

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

3-(2-Chloroethyl)-6,7,8,9-Tetrahydro-9-Hydroxy-2-Methyl-4H-Pyrido[1,2-A]Pyrimidin-4-One is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is critical for research and development in medicinal chemistry, particularly in the synthesis of novel therapeutic agents targeting the central nervous system. It is primarily utilized by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic research institutions engaged in drug discovery programs.

Application

  • Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, especially for neurological and psychiatric applications.
  • Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to develop new molecules with optimized biological activity.
  • Active Pharmaceutical Ingredient (API) Development: Serves as a precursor in the multi-step synthesis of complex APIs for preclinical and clinical studies.
  • Biochemical Research: Employed as a tool compound to study specific enzyme interactions or receptor binding mechanisms.
  • Fine Chemical Synthesis: Utilized in custom synthesis and contract manufacturing for specialized, high-value chemical products.

Basic Information

Item Details
Product Name 3-(2-Chloroethyl)-6,7,8,9-Tetrahydro-9-Hydroxy-2-Methyl-4H-Pyrido[1,2-A]Pyrimidin-4-One
CAS No. 130049-82-0
Molecular Formula C12H15ClN2O2
Molecular Weight 254.71 g/mol
Synonyms 9-Hydroxy-2-methyl-3-(2-chloroethyl)-6,7,8,9-tetrahydro-4H-pyrido[1,2-a]pyrimidin-4-one; 3-(2-Chloroethyl)-9-hydroxy-2-methyl-6,7,8,9-tetrahydro-4H-pyrido[1,2-a]pyrimidin-4-one; L-689,560; L689560; (9R)-9-Hydroxy-2-methyl-3-(2-chloroethyl)-6,7,8,9-tetrahydro-4H-pyrido[1,2-a]pyrimidin-4-one
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Quality Control

Our 3-(2-Chloroethyl)-6,7,8,9-Tetrahydro-9-Hydroxy-2-Methyl-4H-Pyrido[1,2-A]Pyrimidin-4-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) documenting all critical quality attributes are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This compound is light-sensitive (store away from light) and hygroscopic (moisture-sensitive). Keep the container tightly sealed under an inert atmosphere if specified for long-term storage.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Identification (HPLC) Retention time matches reference standard
Assay (HPLC) ≥ 98.0%
Related Substances (HPLC) Total impurities ≤ 2.0%
Any single unknown impurity ≤ 0.5%
Loss on Drying ≤ 0.5%
Residue on Ignition ≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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