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n-[2-[4-[Bis(2-Chloroethyl)Amino]Phenyl]Sulfanylethyl]Acridin-9-Amine CAS NO 130031-48-0


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CAS No.:130031-48-0

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

n-[2-[4-[Bis(2-Chloroethyl)Amino]Phenyl]Sulfanylethyl]Acridin-9-Amine is a specialized organic compound belonging to the acridine and nitrogen mustard chemical families. This compound matters for its role as a key synthetic intermediate and research chemical in the development of novel therapeutic agents and biochemical probes. It is primarily needed by pharmaceutical R&D laboratories, academic research institutions, and fine chemical manufacturers focused on oncology and targeted drug discovery.

Application

  • Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel acridine-based chemotherapeutic agents and targeted cancer therapies.
  • Biochemical Research: Used as a model compound in studies of DNA intercalation, alkylating agent mechanisms, and structure-activity relationships (SAR) for anticancer activity.
  • Antitumor Agent Development: Investigated for its potential as a precursor in the development of prodrugs and conjugates designed for selective tumor targeting.
  • Academic & Industrial R&D: Employed in organic synthesis and medicinal chemistry research to explore new heterocyclic compounds with potential biological activity.
  • Reference Standard: Can be utilized as a high-purity analytical standard for method development and quality control in related API manufacturing.

Basic Information

Item Details
Product Name n-[2-[4-[Bis(2-Chloroethyl)Amino]Phenyl]Sulfanylethyl]Acridin-9-Amine
CAS No. 130031-48-0
Molecular Formula C25H25Cl2N3S
Molecular Weight 478.45 g/mol
Synonyms 9-Amino-N-[2-[[4-[bis(2-chloroethyl)amino]phenyl]thio]ethyl]acridine; Acridine-9-amine, N-[2-[[4-[bis(2-chloroethyl)amino]phenyl]thio]ethyl]-; 130031-48-0; Acridine mustard derivative; Nitrogen mustard-acridine conjugate; NSC 366140 (related); Potential research code compounds. Contact for additional trade names.
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Quality Control

Our n-[2-[4-[Bis(2-Chloroethyl)Amino]Phenyl]Sulfanylethyl]Acridin-9-Amine is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, MS). We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical parameters to ensure compliance with your research or development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep the container sealed to protect from moisture. For long-term storage, consider inert atmosphere conditions to maximize stability.

Specification

Item Specification
Appearance Yellow to orange solid
Identification (HPLC) Conforms
Identification (IR) Conforms
Purity (HPLC) ≥ 95.0%
Related Substances (HPLC) Individual impurity ≤ 1.0%
Total Impurities ≤ 5.0%
Residual Solvents (GC) Complies with ICH Q3C guidelines
Water Content (KF) ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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