Description

(3R)-1-(Dimethylphenylsilyl)-1-Buten-3-Olacetate CAS NO 129921-47-7 is a high-purity, chiral organosilicon compound characterized by its specific stereochemistry at the 3-position. This compound serves as a valuable chiral building block and intermediate in advanced organic synthesis, particularly for the construction of complex molecules with defined three-dimensional structures. It is primarily utilized by research institutions and industrial R&D departments in the pharmaceutical, agrochemical, and specialty chemical sectors for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of potential drug candidates, especially in asymmetric synthesis routes.
• Agrochemical Research: Used in the development of chiral pesticides and herbicides where specific stereochemistry is crucial for biological activity.
• Advanced Material Synthesis: Building block for creating novel organosilicon polymers and functional materials with tailored properties.
• Catalyst Ligand Precursor: Serves as a starting material for the preparation of chiral ligands used in asymmetric catalysis.
• Academic & Industrial R&D: Essential reagent for methodological development in organic chemistry and process chemistry optimization.
• Fine Chemical Production: Intermediate in the multi-step synthesis of high-value, complex fine chemicals and flavors/fragrances.

Basic Information

Item	Details
Product Name	(3R)-1-(Dimethylphenylsilyl)-1-Buten-3-Olacetate
CAS No.	129921-47-7
Molecular Formula	C14H20O2Si
Molecular Weight	248.40 g/mol
Synonyms	(3R)-1-(Dimethylphenylsilyl)-1-buten-3-yl acetate; (R)-1-(Dimethyl(phenyl)silyl)but-1-en-3-yl acetate; 1-Buten-3-ol, 1-(dimethylphenylsilyl)-, acetate, (3R)-; Acetic acid (3R)-1-(dimethylphenylsilyl)-1-buten-3-yl ester; Chiral silyl enol ether acetate; (R)-Silyl Enol Ether Acetate; DMPS-Butenol Acetate (R-isomer)
EINECS	Contact for details

Quality Control

Our production of (3R)-1-(Dimethylphenylsilyl)-1-Buten-3-Olacetate adheres to stringent quality protocols to ensure batch-to-batch consistency and high chiral purity. Each lot is characterized using advanced analytical techniques including chiral HPLC, GC, NMR, and optical rotation measurement. A comprehensive Certificate of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profile is provided with every shipment, supporting compliance with cGMP and ISO 9001 standards for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0% ee
Specific Optical Rotation	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.