Description

N,n-Dimethylformamide Bis[2-(Trimethyl- Silyl)Ethyl] Acetate is a specialized organosilicon reagent featuring a protected acetate group. This compound is valued for its role as a versatile synthetic intermediate, particularly in advanced organic synthesis and materials science where controlled reactivity and moisture-sensitive functional groups are required. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Advanced Organic Synthesis: Serves as a key building block for the introduction of protected carboxylate and silyl-protected alcohol functionalities in complex molecule assembly.
• Pharmaceutical Intermediates: Used in the research and development of active pharmaceutical ingredients (APIs), particularly for compounds requiring selective deprotection strategies.
• Agrochemical Synthesis: Employed in the synthesis of novel pesticides and herbicides where specific silicon-containing moieties are desired for bioactivity or stability.
• Polymer & Materials Science: Acts as a monomer or cross-linking agent in the development of specialty silicones and functional polymers with tailored properties.
• Peptide Chemistry: Can be utilized for the protection of carboxylic acid groups during solid-phase peptide synthesis (SPPS).
• Chemical Research: A valuable reagent for methodological development in organometallic and silicon chemistry within academic and industrial R&D laboratories.

Basic Information

Product Name	N,n-Dimethylformamide Bis[2-(Trimethyl- Silyl)Ethyl] Acetate
CAS No.	129816-49-5
Molecular Formula	C15H33NO3Si2
Molecular Weight	331.60 g/mol
Synonyms	Acetic acid, 2,2-bis[2-(trimethylsilyl)ethyl]-, N,N-dimethylamide; DMF-BTSEA; Bis(2-(trimethylsilyl)ethyl) acetate dimethylamide; N,N-Dimethyl-2,2-bis[2-(trimethylsilyl)ethyl]acetamide; 129816-49-5; Protected acetate dimethylformamide derivative; Organosilicon protected acetate amide
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Each batch of N,n-Dimethylformamide Bis[2-(Trimethyl- Silyl)Ethyl] Acetate is analyzed using advanced techniques including NMR, HPLC, and GC to confirm identity, purity, and the absence of critical impurities. Certificates of Analysis (COA) are available upon request and provide full traceability and batch-specific data.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.