Description

Satraplatin CAS NO 129580-63-8 is a third-generation platinum-based antineoplastic agent and a member of the platinum coordination complex family. This compound is significant for its oral bioavailability, a key advancement over earlier intravenous platinum chemotherapeutics, offering potential for improved patient convenience and treatment regimens. It is primarily required by pharmaceutical research and development organizations engaged in oncology drug discovery and preclinical studies targeting solid tumors.

Application

• Oncology Research & Drug Development: As a key investigational compound for studying novel platinum-based chemotherapy mechanisms and overcoming cisplatin resistance.
• Preclinical Studies: Utilized in in vitro and in vivo models to evaluate antitumor efficacy, pharmacokinetics, and toxicity profiles.
• Biochemical Research: Serves as a reference standard and active pharmaceutical ingredient (API) intermediate in the synthesis and analysis of platinum complexes.
• Mechanistic Studies: Investigation of DNA binding properties, cell cycle arrest, and apoptosis induction in cancer cell lines.

Basic Information

Product Name	Satraplatin
CAS No.	129580-63-8
Molecular Formula	C10H22N2O4Pt
Molecular Weight	501.40 g/mol
Synonyms	JM-216; BMS-182751; (OC-6-43)-Bis(acetato)amminedichlorocyclohexylamineplatinum(IV); Cyclohexylamine-dichlorodiacetatoplatinum(IV); Satraplatinum; Azane; Azane; Azane
EINECS	Contact for details

Quality Control

Our Satraplatin is produced and handled under strict quality management protocols. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing specifications such as assay (by HPLC), related substances, and residual solvents are available upon request to support your regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.