Description

Methyl 4-[(1R)-1-Hydroxyethyl]Benzoate is a chiral benzoate derivative of significant interest in advanced organic synthesis. This compound serves as a versatile chiral building block and intermediate for the production of high-value, optically active pharmaceuticals and fine chemicals. It is particularly valuable for research and development chemists and process engineers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce specific stereochemistry into complex molecules.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), especially in cardiovascular and central nervous system (CNS) drug candidates.
• Asymmetric Synthesis: Utilized as a starting material or resolving agent in catalytic asymmetric reactions to construct stereogenic centers.
• Liquid Crystal & OLED Materials: Serves as a precursor in the development of chiral dopants for liquid crystal displays and organic light-emitting diode (OLED) materials.
• Agrochemical Synthesis: Intermediate in the production of chiral herbicides, fungicides, and plant growth regulators with enhanced efficacy.
• Flavor & Fragrance Industry: Potential precursor for the synthesis of enantiomerically pure aroma chemicals and flavor compounds.
• Academic & Contract Research: Used in university and CRO laboratories for methodological development in stereoselective organic chemistry.

Basic Information

Product Name	Methyl 4-[(1R)-1-Hydroxyethyl]Benzoate
CAS No.	129446-47-5
Molecular Formula	C10H12O3
Molecular Weight	180.20 g/mol
Synonyms	(R)-Methyl 4-(1-Hydroxyethyl)benzoate; Methyl (R)-4-(1-Hydroxyethyl)benzoate; Benzoic acid, 4-[(1R)-1-hydroxyethyl]-, methyl ester; (R)-(-)-Methyl 4-(1-Hydroxyethyl)benzoate; p-[(1R)-1-Hydroxyethyl]methyl benzoate; (R)-Methyl p-(1-hydroxyethyl)benzoate; Methyl (R)-(-)-4-(1-Hydroxyethyl)benzoate
EINECS	Contact for details

Quality Control

Our Methyl 4-[(1R)-1-Hydroxyethyl]Benzoate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity determination by HPLC, to ensure it meets the high standards required for synthetic applications. Certificates of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.