Description

Sbfi-Am is a high-purity, specialized chemical compound widely recognized for its role as a potent and selective inhibitor of the sodium-bicarbonate cotransporter (NBC). This compound is essential for researchers and developers in life sciences, enabling precise modulation of cellular pH regulation and ion transport mechanisms. It is a critical tool for biochemical research, pharmaceutical development, and diagnostic applications where understanding bicarbonate transport is paramount.

Application

• Biochemical Research: A key pharmacological tool for studying the function and inhibition of sodium-bicarbonate cotransporters (NBC) in cellular and molecular biology.
• Pharmaceutical R&D: Used in drug discovery programs targeting conditions related to pH dysregulation, such as certain cancers, metabolic disorders, and renal diseases.
• Physiological Studies: Employed in experimental models to investigate acid-base homeostasis, electrolyte balance, and related physiological pathways.
• Diagnostic Development: Serves as a reference standard or active component in the development of assays and diagnostic kits for research purposes.
• Neuroscience Research: Applied in studies exploring the role of bicarbonate transport in neuronal function and central nervous system physiology.

Basic Information

Product Name	Sbfi-Am
CAS No.	129423-53-6
Molecular Formula	C₂₅H₂₂N₂O₁₃S₂
Molecular Weight	622.58 g/mol
Synonyms	SBFI-AM; SBFI AM; SBFI Acetoxymethyl Ester; Sodium-binding benzofuran isophthalate acetoxymethyl ester; 1,3-Benzenedicarboxylic acid, 4,4'-[1,4,10,13-tetraoxa-7,16-diazacyclooctadecane-7,16-diylbis(5-methoxy-6,1-benzofurandiyl)]bis-, tetrakis[(acetyloxy)methyl] ester
EINECS	Contact for details

Quality Control

Our Sbfi-Am is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity verification and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research applications. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and consistent performance.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to warm to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	Yellow to orange solid or film
Identification (HPLC/IR)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Solubility	Soluble in DMSO, DMF

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.