Description

4-Oxazolidineacetic Acid, 2,5-Dioxo-, 1,1-Dimethylethyl Ester, (4S)- is a high-value, stereochemically defined chiral building block used in advanced organic synthesis. Its core value proposition lies in providing a protected, enantiomerically pure scaffold for constructing complex molecules with precise three-dimensional architecture. This compound is essential for researchers and manufacturers in the pharmaceutical and fine chemical industries, particularly for developing active pharmaceutical ingredients (APIs) and novel agrochemicals where stereochemistry is critical for efficacy.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of complex drug candidates, especially those containing β-amino acid or heterocyclic motifs.
• Peptidomimetic Research: Used to construct conformationally constrained peptide analogs and protease inhibitors.
• Agrochemical Synthesis: Serves as a building block for creating enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Asymmetric Catalysis Ligand Precursor: Can be utilized to develop novel chiral ligands and organocatalysts.
• Academic & R&D: Employed in medicinal chemistry and synthetic methodology research for exploring new chemical space.
• Fine Chemical Production: Integral to the multi-step synthesis of specialty chemicals requiring high stereochemical purity.

Basic Information

Item	Detail
Product Name	4-Oxazolidineacetic Acid, 2,5-Dioxo-, 1,1-Dimethylethyl Ester, (4S)-
CAS No.	129288-31-9
Molecular Formula	C9H13NO5
Molecular Weight	215.20 g/mol
Synonyms	(4S)-1-(tert-Butoxycarbonyl)-2,5-dioxo-4-oxazolidineacetic acid; (S)-1-(tert-Butoxycarbonyl)-2,5-dioxooxazolidine-4-acetic acid; (S)-N-Boc-2,5-dioxooxazolidine-4-acetic acid; (S)-4-(Carboxymethyl)-1,3-oxazolidine-2,5-dione, 1-tert-butyl ester; (S)-1-Boc-2,5-dioxooxazolidine-4-acetic acid; tert-Butyl (4S)-2,5-dioxo-4-oxazolidineacetate; (S)-Boc-DOA-OH; Chiral Oxazolidinedione Derivative
EINECS	Contact for details

Quality Control

Our production of 4-Oxazolidineacetic Acid, 2,5-Dioxo-, 1,1-Dimethyl Ester, (4S)- adheres to stringent quality protocols to ensure batch-to-batch consistency and high enantiomeric purity. Each lot is characterized using advanced analytical techniques including chiral HPLC, NMR, and mass spectrometry. Certificates of Analysis (COA) detailing purity, enantiomeric excess, and impurity profiles are provided with every shipment. We operate under a quality management system and can support development projects requiring ICH stability data or custom specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound may be moisture-sensitive; keep the container tightly sealed under an inert atmosphere if specified. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.