Description

1-Oxaspiro[2.5]Octane-2-Methanol, (2S)- is a high-purity, chiral spirocyclic building block with significant synthetic utility. This compound is valued for its unique three-dimensional structure, which is crucial for imparting specific stereochemistry and conformational rigidity in advanced molecular architectures. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications in asymmetric synthesis and the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Asymmetric Catalysis Ligand Precursor: Used in the development of novel chiral ligands and organocatalysts for enantioselective transformations.
• Agrochemical Research: Serves as a building block for creating novel pesticides and herbicides with enhanced stereospecific activity.
• Material Science: Employed in the research of specialty polymers and advanced organic materials requiring rigid, spirocyclic motifs.
• Academic & Industrial R&D: A valuable tool for methodological studies in organic synthesis and medicinal chemistry programs.

Basic Information

Item	Details
Product Name	1-Oxaspiro[2.5]Octane-2-Methanol, (2S)-
CAS No.	129100-11-4
Molecular Formula	C8H14O2
Molecular Weight	142.20 g/mol
Synonyms	(2S)-1-Oxaspiro[2.5]octane-2-methanol; (S)-1-Oxaspiro[2.5]octane-2-methanol; (2S)-1-Oxaspiro[2.5]octan-2-ylmethanol; (S)-Oxaspirooctanemethanol; (2S)-Oxaspiro[2.5]octane-2-methanol; (S)-Spirocyclic oxirane methanol derivative; (2S)-2-(Hydroxymethyl)-1-oxaspiro[2.5]octane
EINECS	Contact for details

Quality Control

Our 1-Oxaspiro[2.5]Octane-2-Methanol, (2S)- is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity assessment by HPLC, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing identity, purity, and enantiomeric excess are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept tightly sealed in a dry environment to prevent moisture uptake, which may affect stability and handling.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.