Description

21-Fluoropromegestone is a synthetic progestin steroid derivative, recognized for its high potency and selectivity. This compound is a critical intermediate and reference standard in pharmaceutical research and development, particularly for studying progesterone receptor activity. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and advanced chemical synthesis sectors who require high-purity, well-characterized bioactive molecules.

Application

• Pharmaceutical Reference Standard: Used as a certified standard for quality control and analytical method development in drug manufacturing.
• Endocrinology Research: A key tool for in vitro and in vivo studies targeting the progesterone receptor, aiding in the understanding of hormonal pathways.
• Drug Discovery & Development: Serves as a crucial intermediate or lead compound in the synthesis of novel therapeutic agents for hormonal disorders.
• Biochemical Assays: Employed in receptor binding assays and other high-throughput screening platforms to evaluate progestogenic activity.
• Academic Research: Utilized in university and institutional labs for fundamental research in steroid chemistry and molecular biology.
• Veterinary Medicine: Potential applications in the development of hormonal treatments for animals.

Basic Information

Product Name	21-Fluoropromegestone
CAS No.	128855-74-3
Molecular Formula	C₂₂H₂₉FO₃
Molecular Weight	360.47 g/mol
Synonyms	21-Fluoro-16α-ethyl-19-norpregn-4-ene-3,20-dione; 21-Fluoro-16α-ethyl-19-norprogesterone; 21-F-Promegestone; 21-Fluoropromegestone; 16α-Ethyl-21-fluoro-19-norpregn-4-ene-3,20-dione; RS-5020 (Fluorinated analog); Fluorinated Promegestone
EINECS	Contact for details

Quality Control

Our 21-Fluoropromegestone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. A detailed Certificate of Analysis (COA) is provided with every shipment, ensuring traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.