Description

Estrone 3-Valerate is a specific ester derivative of the natural estrogen, estrone. This compound is of significant interest in pharmaceutical research and development, particularly for its potential as a prodrug or as an intermediate in the synthesis of more complex steroidal molecules. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of hormone therapies and novel drug delivery systems. The precise chemical structure of Estrone 3-Valerate CAS NO 128788-26-1 allows for targeted modifications to optimize pharmacokinetic properties.

Application

• Pharmaceutical Intermediate: A key starting material or intermediate in the multi-step synthesis of steroidal active pharmaceutical ingredients (APIs) and prodrugs.
• Biochemical Research: Used in laboratory studies to investigate estrogen receptor binding, metabolic pathways, and the structure-activity relationships of estrogen derivatives.
• Reference Standard: Serves as an analytical standard in quality control laboratories for the identification and quantification of related compounds using techniques like HPLC and GC-MS.
• Prodrug Development: Investigated for its utility in creating lipophilic prodrugs designed to enhance absorption and bioavailability of estrogenic compounds.

Basic Information

Product Name	Estrone 3-Valerate
CAS No.	128788-26-1
Molecular Formula	C24H32O4
Molecular Weight	384.51 g/mol
Synonyms	Estrone Valerate; 3-Hydroxyestra-1,3,5(10)-trien-17-one 3-valerate; Estra-1,3,5(10)-trien-17-one, 3-(1-oxopentoxy)-, (17β)-; Estrone pentanoate; Oestrone valerate; Estrone 3-O-valerate
EINECS	Contact for details

Quality Control

Our Estrone 3-Valerate is produced and handled under strict quality management protocols to ensure batch-to-batch consistency and high purity, suitable for research and development purposes. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards and can provide material tailored to specific project requirements upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.