Description

Lychnostatin 1 is a potent and specific inhibitor of phospholipase A2, a key enzyme involved in inflammatory pathways. This high-purity biochemical tool is essential for researchers and developers in life sciences, enabling precise modulation of arachidonic acid metabolism for mechanistic studies. It serves as a critical compound for pharmaceutical R&D, particularly in the investigation of anti-inflammatory drug candidates and cellular signaling mechanisms.

Application

• Pharmaceutical Research & Development: Used as a reference standard and active pharmacological agent in the discovery and validation of novel anti-inflammatory therapeutics.
• Biochemical Assay Development: Serves as a key inhibitor in enzymatic assays to study phospholipase A2 (PLA2) activity and inhibition kinetics.
• Cell Biology & Signal Transduction Studies: Employed to investigate the role of PLA2 in cellular processes such as eicosanoid production, membrane remodeling, and inflammatory responses.
• Academic Research: A vital tool for universities and research institutes studying inflammation, lipid metabolism, and related disease models.
• Preclinical Studies: Utilized in animal models to evaluate the efficacy and mechanism of action of compounds targeting the arachidonic acid cascade.

Basic Information

Product Name	Lychnostatin 1
CAS No.	128700-83-4
Molecular Formula	C45H78N8O11
Molecular Weight	883.2 g/mol
Synonyms	Lychnostatine 1; Phospholipase A2 Inhibitor Lychnostatin 1; (2S)-2-[[(2S,3R,4E)-3-Hydroxy-2-[[(2S,3S)-3-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-Amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]-3-phenylpropanoyl]amino]-3-hydroxybutanoyl]amino]-1-oxo-4-octadecenyl]amino]-3-phenylpropanoic Acid; PLA2 Inhibitor from Lychnostatine Family.
EINECS	Contact for details

Quality Control

Our Lychnostatin 1 is produced under stringent conditions to ensure batch-to-batch consistency and high biological activity. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting purity, potency, and other critical quality attributes to support your research and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below. Allow the product to equilibrate to room temperature before opening to minimize moisture condensation. The container should be kept in a dry, well-ventilated area designated for research chemicals.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Biological Activity (PLA2 Inhibition Assay)	IC50 provided on COA

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.