Description

8-[4-(4-Fluorophenyl)-4,4-(Ethylendioxy)Butyl]-3-[2'-(2,4,6-Trimethylphenylsulfonyloxyethyl)]-1-Phenyl-1,3,8-Triazaspiro[4.5]Decan-4-One is a high-purity, complex organic intermediate of significant interest in advanced pharmaceutical synthesis. This compound is valued for its intricate molecular architecture, which serves as a key building block in the development of novel active pharmaceutical ingredients (APIs). It is primarily sought by research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers engaged in the synthesis of specialized therapeutic agents.

Application

This advanced chemical intermediate is designed for specialized synthetic applications, particularly in pharmaceutical research and development.

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of novel drug candidates, especially in central nervous system (CNS) and receptor-targeted therapies.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Process Chemistry Development: Serves as a key intermediate for scaling up synthetic routes from laboratory to pilot plant and commercial production.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for the production of bespoke compounds for client projects.
• Academic Research: Utilized in university and institutional labs for studying complex organic reactions and heterocyclic chemistry.

Basic Information

Product Name	8-[4-(4-Fluorophenyl)-4,4-(Ethylendioxy)Butyl]-3-[2'-(2,4,6-Trimethylphenylsulfonyloxyethyl)]-1-Phenyl-1,3,8-Triazaspiro[4.5]Decan-4-One
CAS No.	128584-73-6
Molecular Formula	C34H40FN3O5S
Molecular Weight	621.77 g/mol
Synonyms	1,3,8-Triazaspiro[4.5]decan-4-one, 8-[4-(4-fluorophenyl)-4,4-(ethylenedioxy)butyl]-3-[2-[(2,4,6-trimethylphenyl)sulfonyl]oxy]ethyl]-1-phenyl-; Spirocyclic Fluorophenyl Sulfonate Ester; 128584-73-6; 8-[4-(4-Fluorophenyl)-4,4-(ethylenedioxy)butyl]-3-[2-[(2,4,6-trimethylphenyl)sulfonyl]oxy]ethyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one; Triazaspirodecanone derivative; Fluorophenyl-triazaspiro intermediate.
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems. Each batch undergoes comprehensive analytical characterization to ensure identity, purity, and consistency. Certificates of Analysis (COA) are provided, detailing results from HPLC, NMR, and mass spectrometry. We support cGMP-compliant manufacturing for pharmaceutical applications, and specifications can be aligned with client-specific requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider inert gas purging.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.