Description

(S)-(+)-1,1'-Bi-2-Naphthyl Di-p-Toluenesulfonate is a high-value chiral intermediate and resolving agent, widely recognized for its utility in asymmetric synthesis. This compound is critical for the preparation of enantiomerically pure compounds, enabling the production of pharmaceuticals and advanced materials with high optical purity. It is essential for research and development chemists, process engineers, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries who require reliable, high-quality chiral building blocks.

Application

• Chiral Resolution Agent: Employed for the kinetic resolution of racemic mixtures and the separation of enantiomers in pharmaceutical synthesis.
• Asymmetric Synthesis Catalyst Precursor: Serves as a key ligand precursor for metal-catalyzed asymmetric transformations, such as hydrogenations and cross-coupling reactions.
• Pharmaceutical Intermediate: Used in the synthesis of active pharmaceutical ingredients (APIs) that require a specific (S)-configuration for optimal biological activity.
• Material Science Research: Acts as a monomer or building block for developing chiral polymers and advanced organic materials with specific optical properties.
• Agrochemical Development: Utilized in creating enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Academic & Industrial R&D: A fundamental reagent for methodological development in organic chemistry and process optimization studies.

Basic Information

Product Name	(S)-(+)-1,1'-Bi-2-Naphthyl Di-p-Toluenesulfonate
CAS No.	128575-35-9
Molecular Formula	C34H26O6S2
Molecular Weight	594.69 g/mol
Synonyms	(S)-BINOL Di-p-toluenesulfonate; (S)-(+)-1,1'-Bi-2-naphthol Ditosylate; (S)-BINOL-Ditosylate; (S)-1,1'-Binaphthyl-2,2'-diyl Di-p-toluenesulfonate; (S)-2,2'-Bis(p-toluenesulfonyloxy)-1,1'-binaphthyl; (S)-DTB; (S)-BINOL-OTs; (S)-BINOL Tosylate
EINECS	Contact for details

Quality Control

Our (S)-(+)-1,1'-Bi-2-Naphthyl Di-p-Toluenesulfonate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure compliance with exacting standards for research and industrial use. A comprehensive Certificate of Analysis (COA) detailing purity, enantiomeric excess, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (ee)	≥ 99.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.