Description

Cyclopropanecarboxylic Acid, 2-(Bromoacetyl)-, Methyl Ester, trans- (9Ci) is a high-purity, specialized organic building block featuring a reactive bromoacetyl group attached to a trans-substituted cyclopropane ring. This compound matters for its unique structural motif, which is highly valuable in the synthesis of complex molecules for pharmaceutical and agrochemical research. It is primarily needed by R&D chemists and process development scientists working on novel active ingredients, particularly in medicinal chemistry where the cyclopropane scaffold is prized for its conformational rigidity and metabolic stability.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, especially those targeting central nervous system (CNS) disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides, where the cyclopropane moiety can enhance biological activity and environmental stability.
• Chemical Biology Probe Development: Serves as a versatile scaffold for constructing molecular probes to study enzyme function and protein-ligand interactions due to its reactive handle.
• Material Science Research: Employed in the synthesis of specialty monomers or ligands for catalysts and advanced polymeric materials.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific, multi-step synthetic routes.

Basic Information

Product Name	Cyclopropanecarboxylic Acid, 2-(Bromoacetyl)-, Methyl Ester, trans- (9Ci)
CAS No.	128515-13-9
Molecular Formula	C7H9BrO3
Molecular Weight	221.05 g/mol
Synonyms	trans-2-(Bromoacetyl)cyclopropanecarboxylic Acid Methyl Ester; Methyl trans-2-(Bromoacetyl)cyclopropanecarboxylate; (1R,2S)-rel-2-(Bromoacetyl)cyclopropanecarboxylic Acid Methyl Ester; Bromoacetyl Cyclopropane Carboxylate Methyl Ester; Cyclopropanecarboxylic acid, 2-(bromoacetyl)-, methyl ester, trans-; (1R,2S)-2-(2-Bromoacetyl)cyclopropane-1-carboxylic acid methyl ester; trans-Methyl 2-(bromoacetyl)cyclopropanecarboxylate
EINECS	Contact for details

Quality Control

Our Cyclopropanecarboxylic Acid, 2-(Bromoacetyl)-, Methyl Ester, trans- (9Ci) is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific client or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0% (Standard Grade)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.