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6-Deoxy-β-L-Galactopyranose 2,3,4-Triacetate 1-[Bis(Phenylmethyl) Phosphate] CAS NO 128473-05-2


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CAS No.:128473-05-2

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

6-Deoxy-β-L-Galactopyranose 2,3,4-Triacetate 1-[Bis(Phenylmethyl) Phosphate] is a high-purity, protected carbohydrate derivative designed for advanced synthetic applications. This compound serves as a critical glycosyl donor or intermediate in the stereoselective synthesis of complex oligosaccharides and glycoconjugates. It is essential for research and development in pharmaceutical discovery, particularly for creating novel therapeutics, vaccines, and diagnostic agents that target carbohydrate-mediated biological processes.

Application

  • Pharmaceutical Intermediate: Key building block for the synthesis of novel glycosylated drugs, including antibiotics, antivirals, and anticancer agents.
  • Glycobiology Research: Used as a precursor in enzymatic or chemical glycosylation studies to investigate cell signaling, immune response, and disease mechanisms.
  • Carbohydrate Chemistry: Serves as a protected glycosyl donor in the laboratory-scale and pilot-scale synthesis of complex oligosaccharides and glycoconjugates.
  • Vaccine Development: Employed in the construction of synthetic carbohydrate antigens for conjugate vaccine candidates against bacterial pathogens.
  • Diagnostic Reagent Synthesis: Utilized to create labeled glycans or glycan arrays for diagnostic assays and biomarker discovery.
  • Process Development: Acts as a reference standard or starting material for scaling up glycosylation reactions in process chemistry.

Basic Information

Product Name 6-Deoxy-β-L-Galactopyranose 2,3,4-Triacetate 1-[Bis(Phenylmethyl) Phosphate]
CAS No. 128473-05-2
Molecular Formula C26H31O11P
Molecular Weight 550.50 g/mol
Synonyms 1-O-(Dibenzylphospho)-2,3,4-tri-O-acetyl-6-deoxy-β-L-galactopyranose; 6-Deoxy-β-L-galactopyranose 2,3,4-triacetate 1-(dibenzyl phosphate); Dibenzyl (2,3,4-tri-O-acetyl-6-deoxy-β-L-galactopyranosyl) phosphate; β-L-Fucopyranose 2,3,4-triacetate 1-(dibenzyl phosphate) (stereoisomer); Protected β-L-Fucose derivative; Glycosyl phosphate donor; Dibenzylphosphoryl glycoside.
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Quality Control

Our 6-Deoxy-β-L-Galactopyranose 2,3,4-Triacetate 1-[Bis(Phenylmethyl) Phosphate] is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and pharmaceutical development. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions or a dry inert atmosphere to maintain stability and purity. Allow the sealed container to equilibrate to room temperature before opening to prevent moisture condensation.

Specification

Item Specification
Appearance White to off-white solid
Identification (IR) Conforms to structure
Identification (NMR) Conforms to structure
Purity (HPLC) ≥ 95.0%
Water Content (KF) ≤ 1.0%
Residual Solvents (GC) Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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