Description

L-Alanine, n-(Cyanomethyl)-, Ethyl Ester (9Ci) is a specialized amino acid derivative characterized by its cyano and ester functional groups. This molecular structure makes it a valuable non-natural building block for the synthesis of complex peptides and other bioactive molecules. It is primarily utilized by research institutions and pharmaceutical companies engaged in medicinal chemistry and advanced organic synthesis.

Application

• Pharmaceutical Intermediates: Serves as a key chiral synthon in the research and development of novel active pharmaceutical ingredients (APIs).
• Peptide Synthesis: Used as a modified amino acid building block for introducing specific functional groups into synthetic peptide chains.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies and the creation of compound libraries for drug discovery.
• Bioconjugation Chemistry: Acts as a linker or spacer molecule in the development of antibody-drug conjugates (ADCs) and other bioconjugates.
• Chemical Biology Probes: Utilized in the design and synthesis of probes for studying enzyme mechanisms and biological pathways.
• Agrochemical Research: Investigated as a potential intermediate for the synthesis of novel, biologically active crop protection agents.

Basic Information

Product Name	L-Alanine, n-(Cyanomethyl)-, Ethyl Ester (9Ci)
CAS No.	128427-04-3
Molecular Formula	C7H12N2O2
Molecular Weight	156.18 g/mol
Synonyms	Ethyl N-(cyanomethyl)-L-alaninate; L-Alanine, N-(cyanomethyl)-, ethyl ester; (S)-Ethyl 2-amino-3-(cyanomethylamino)propanoate; Ethyl (2S)-2-amino-3-[(cyanomethyl)amino]propanoate; Alanine derivative, N-cyanomethyl, ethyl ester; Amino acid ester derivative; CAS 128427-04-3
EINECS	Contact for details

Quality Control

Our L-Alanine, n-(Cyanomethyl)-, Ethyl Ester (9Ci) is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We support research and development with material that meets exacting standards for advanced synthetic applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Optical Rotation	Specific range provided on COA
Heavy Metals	< 20 ppm
Residual Solvents	Complies with ICH guidelines
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.