Description

Spiro[Cyclohexane-1,1(5H)-[3H]Oxazolo[4,3-A]Isoquinolin]-3-One, 6,10B-Dihydro-10B-Hydroxy-8,9-Dimethoxy- is a complex spirocyclic organic compound that serves as a high-value synthetic intermediate and building block in advanced chemical synthesis. Its intricate fused-ring structure makes it particularly valuable for the research and development of novel pharmaceutical agents and bioactive molecules. This compound is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in creating new therapeutic candidates.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting neurological or oncological pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new chemical entities.
• Organic Synthesis Reference Standard: Serves as a high-purity standard for analytical method development and validation in QC laboratories.
• Academic & Institutional Research: Employed in universities and research institutes for studying spirocyclic and heterocyclic chemistry.
• Fine Chemical Production: An intermediate for the manufacture of specialized, high-value fine chemicals and advanced materials.
• Biochemical Tool Compound: Potential use as a probe or inhibitor in biochemical assays to study specific biological mechanisms.

Basic Information

Product Name	Spiro[Cyclohexane-1,1(5H)-[3H]Oxazolo[4,3-A]Isoquinolin]-3-One, 6,10B-Dihydro-10B-Hydroxy-8,9-Dimethoxy-
CAS No.	128425-94-5
Molecular Formula	C₁₉H₂₁NO₅
Molecular Weight	343.38 g/mol
Synonyms	6,10b-Dihydro-10b-hydroxy-8,9-dimethoxyspiro[cyclohexane-1,1'(5'H)-[3'H]oxazolo[4,3-a]isoquinolin]-3'-one; 10b-Hydroxy-8,9-dimethoxy-6,10b-dihydro-5H-spiro[cyclohexane-1,1'-[3H]oxazolo[4,3-a]isoquinolin]-3-one; Spiro[cyclohexane-1,1'(5'H)-[3'H]oxazolo[4,3-a]isoquinoline]-3'-one, 6,10b-dihydro-10b-hydroxy-8,9-dimethoxy-; (10bR)-10b-Hydroxy-8,9-dimethoxy-6,10b-dihydro-5H-spiro[cyclohexane-1,1'-[3H]oxazolo[4,3-a]isoquinolin]-3-one (if stereochemistry is defined).
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems. Each batch undergoes comprehensive analytical characterization, including HPLC, NMR, and MS, to ensure identity, purity, and batch-to-batch consistency suitable for research and development applications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). For long-term storage, consider storage under inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.