Description

Platinate(2-), Diamminechloro(n-(n-L-γ-Glutamyl-L-Cysteinyl)Glycin Ato(3-)-S)-, Dihydrogen, (Sp-4-2)- is a specialized platinum(II) complex coordinated with a glutathione-derived tripeptide ligand. This compound is of significant interest in advanced pharmaceutical research and development, particularly for its potential in designing novel metal-based therapeutics and diagnostic agents. Its unique structure, which integrates a biologically relevant peptide, makes it a valuable precursor for investigating targeted drug delivery systems and bio-conjugation strategies in oncology and other therapeutic areas. The CAS number for this compound is 128353-81-1.

Application

• Pharmaceutical Research & Development: As a key intermediate or precursor in the synthesis of novel platinum-based anticancer agents and targeted therapies.
• Bio-conjugation Chemistry: For the development of antibody-drug conjugates (ADCs) or other protein/peptide-linked diagnostic and therapeutic platforms.
• Chemical Biology Probes: Utilized in research to study metal-protein interactions, enzyme inhibition, and cellular uptake mechanisms.
• Catalysis Research: Investigation of its potential as a catalyst or catalyst precursor in specialized organic transformations under mild, biologically relevant conditions.
• Academic & Institutional Research: Serves as a reference standard or starting material for studies in bioinorganic chemistry, medicinal chemistry, and metallodrug design.

Basic Information

Product Name	Platinate(2-), Diamminechloro(n-(n-L-γ-Glutamyl-L-Cysteinyl)Glycin Ato(3-)-S)-, Dihydrogen, (Sp-4-2)-
CAS No.	128353-81-1
Molecular Formula	C10H18ClN5O6PtS
Molecular Weight	598.91 g/mol
Synonyms	Diamminechloro(glutathionato)platinum(II); Platinum(II) glutathione complex; Chloro(glutathionato)(ammine)platinum(II); (SP-4-2)-Diamminechloro(glutathionato-S)platinum; Glutathione platinum complex; L-Glutathione, platinum complex; Pt-GSH complex; Amminechloro(glutathionato)platinum
EINECS	Contact for details

Quality Control

Our Platinate(2-), Diamminechloro(n-(n-L-γ-Glutamyl-L-Cysteinyl)Glycin Ato(3-)-S)-, Dihydrogen, (Sp-4-2)- is produced under strict quality management protocols suitable for research and development applications. Each batch is characterized and tested to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing specifications such as assay (by HPLC), related substances, and residual solvents is provided with every shipment. We support cGMP compliance for advanced pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This material is hygroscopic (moisture-sensitive) and light-sensitive. For long-term storage, consider desiccation and storage under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	Yellow to orange solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Assay (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.