Description

2-(tert-Butyldimethylsilyloxy)Malononitrile is a versatile silyl-protected malononitrile derivative, a key building block in advanced organic synthesis. This compound is valued for its role as a masked active methylene synthon, enabling the controlled introduction of the malononitrile moiety under mild conditions. It is primarily sought by research and development chemists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex heterocycles and fine chemical intermediates.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for heterocyclic compounds with potential biological activity.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its reactivity to form pyridine and other nitrogen-containing ring systems.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of specialty polymers and advanced organic materials.
• Fine Chemical Production: Employed in multi-step syntheses to produce dyes, pigments, and other high-value specialty chemicals.
• Academic & Process R&D: A valuable reagent for methodology development and scaling novel synthetic routes in academic and industrial laboratories.

Basic Information

Product Name	2-(tert-Butyldimethylsilyloxy)Malononitrile
CAS No.	128302-78-3
Molecular Formula	C9H16N2OSi
Molecular Weight	196.32 g/mol
Synonyms	Malononitrile, 2-[(1,1-dimethylethyl)dimethylsilyl]oxy]-; 2-((tert-Butyldimethylsilyl)oxy)malononitrile; TBDMS-protected malononitrile; 2-(TBDMSO)malononitrile; 2-Hydroxymalononitrile TBDMS ether; 2-[(tert-Butyldimethylsilyl)oxy]propanedinitrile
EINECS	Contact for details

Quality Control

Our 2-(tert-Butyldimethylsilyloxy)Malononitrile is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and FTIR, to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, confirming compliance with customer specifications and internal quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases and incompatible materials. The container should be kept tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.