Description

Spiro[1-Azabicyclo[2.2.2]Octane-3,5'(4'H)-Oxazole], 2'-(1-Methyl-1H-Indol-3-Yl)- is a complex spirocyclic organic compound featuring a fused azabicyclooctane and oxazole ring system with an indole substituent. This unique molecular architecture makes it a high-value intermediate or building block for advanced pharmaceutical research and fine chemical synthesis. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced material sectors for creating novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates targeting neurological disorders, leveraging its complex, nitrogen-rich heterocyclic scaffold.
• Agrochemical Research: Used as a building block for developing new pesticides or herbicides with specific biological activity profiles.
• Ligand & Catalyst Development: Employed in organometallic chemistry and catalysis research due to its potential as a chelating or directing ligand.
• Material Science: Investigated for incorporation into advanced organic polymers or frameworks with specialized electronic or optical properties.
• Chemical Biology Probe: Utilized in academic and industrial research to study enzyme inhibition or protein-ligand interactions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthetic projects requiring this specialized structure.

Basic Information

Item	Details
Product Name	Spiro[1-Azabicyclo[2.2.2]Octane-3,5'(4'H)-Oxazole], 2'-(1-Methyl-1H-Indol-3-Yl)-
CAS No.	128199-93-9
Molecular Formula	C17H19N3O
Molecular Weight	281.35 g/mol
Synonyms	2'-(1-Methyl-1H-indol-3-yl)spiro[1-azabicyclo[2.2.2]octane-3,5'-oxazole]; 2-(1-Methylindol-3-yl)spiro[1-azabicyclo[2.2.2]octane-3,5'-oxazole]; Spiro[1-azabicyclo[2.2.2]octane-3,5'-oxazole], 2'-(1-methyl-1H-indol-3-yl)-; 128199-93-9; 2'-(1-Methylindol-3-yl)-1-azaspiro[bicyclo[2.2.2]octane-3,5'-oxazole]; 3-(1-Methyl-1H-indol-3-yl)-1-azaspiro[bicyclo[2.2.2]octane-5,2'-oxazole]
EINECS	Contact for details

Quality Control

Our Spiro[1-Azabicyclo[2.2.2]Octane-3,5'(4'H)-Oxazole], 2'-(1-Methyl-1H-Indol-3-Yl)- is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing specifications such as assay (HPLC), related substances, and physical characteristics are provided and available upon request. We support cGMP standards for advanced intermediate production where required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). This compound may be light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0% Any single unknown impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.