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2-Azidoethyl B-D-Glucopyranosiduronic Acid CAS NO 128095-64-7


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CAS No.:128095-64-7

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

2-Azidoethyl B-D-Glucopyranosiduronic Acid is a specialized glycosyl donor derivative, a key synthetic intermediate in carbohydrate and medicinal chemistry. Its value lies in the reactive azidoethyl group, which serves as a versatile handle for further functionalization via click chemistry, enabling the efficient synthesis of complex glycoconjugates. This compound is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors, particularly for developing novel drug candidates, diagnostic probes, and advanced biomaterials.

Application

  • Glycoconjugate Synthesis: A crucial building block for the preparation of neoglycoconjugates, glycopeptides, and glycolipids via copper-catalyzed azide-alkyne cycloaddition (CuAAC) click chemistry.
  • Pharmaceutical Intermediates: Used in the research and development of carbohydrate-based therapeutics, including antiviral agents, cancer vaccines, and targeted drug delivery systems.
  • Biomaterial Development: Enables the surface functionalization of polymers, nanoparticles, and hydrogels with bioactive sugar moieties to create smart materials for tissue engineering and biosensing.
  • Chemical Biology Probes: Serves as a precursor for synthesizing activity-based probes and metabolic labeling agents to study glycosylation processes and carbohydrate-protein interactions in biological systems.
  • Enzyme Substrate Analog: Acts as a substrate or inhibitor analog for glycosyltransferases and glycosidases, facilitating enzyme mechanism studies and inhibitor design.

Basic Information

Product Name 2-Azidoethyl B-D-Glucopyranosiduronic Acid
CAS No. 128095-64-7
Molecular Formula C8H13N3O7
Molecular Weight 263.21 g/mol
Synonyms 2-Azidoethyl β-D-Glucopyranosiduronic Acid; β-D-Glucopyranosiduronic Acid, 2-azidoethyl; 2-Azidoethyl Glucuronide; Azidoethyl Glucuronate; Glucuronic Acid Azidoethyl Glycoside; 1-(2-Azidoethoxy)-β-D-glucopyranuronic acid; (2R,3S,4S,5R,6R)-6-(2-Azidoethoxy)-3,4,5-trihydroxyoxane-2-carboxylic acid
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Quality Control

Our 2-Azidoethyl B-D-Glucopyranosiduronic Acid is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure traceability and compliance with your research or cGMP starting material requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation and ensure long-term stability. The material is moisture-sensitive; keep the container tightly sealed in a dry environment. Allow the sealed container to equilibrate to room temperature before opening to minimize condensation.

Specification

Item Specification
Appearance White to off-white solid
Identification (IR) Conforms to structure
Identification (NMR) Conforms to structure
Purity (HPLC) ≥ 95.0%
Water Content (KF) ≤ 2.0%
Residual Solvents (GC) Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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