Description

3-Chloropyridine-2-Carboxylic Acid Ethyl Ester is a high-purity, versatile pyridine derivative ester that serves as a critical building block in advanced organic synthesis. Its unique halogenated structure makes it an essential intermediate for constructing complex molecules with targeted biological and chemical properties. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, particularly in the development of kinase inhibitors, antiviral agents, and other bioactive heterocyclic compounds.
• Agrochemical Synthesis: Used in the production of advanced pesticides, herbicides, and fungicides, where the chloropyridine moiety contributes to efficacy and selectivity.
• Ligand and Catalyst Preparation: Serves as a precursor for creating specialized ligands used in metal-catalyzed cross-coupling reactions and other catalytic processes.
• Material Science Research: Employed in the development of organic electronic materials, liquid crystals, and functional polymers.
• Custom Synthesis and Contract Manufacturing: A valuable starting material for custom synthesis projects and scale-up production under cGMP or ISO standards.

Basic Information

Product Name	3-Chloropyridine-2-Carboxylic Acid Ethyl Ester
CAS No.	128073-20-1
Molecular Formula	C8H8ClNO2
Molecular Weight	185.61 g/mol
Synonyms	Ethyl 3-Chloropyridine-2-carboxylate; 3-Chloro-2-pyridinecarboxylic Acid Ethyl Ester; 2-Carbethoxy-3-chloropyridine; 3-Chloropicolinic Acid Ethyl Ester; Ethyl 3-Chloropicolinate; 3-Chloro-2-(ethoxycarbonyl)pyridine; 3-Chloropyridine-2-carboxylic Acid Ethyl Ester
EINECS	Contact for details

Quality Control

Our 3-Chloropyridine-2-Carboxylic Acid Ethyl Ester is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, GC for residual solvents, and NMR/IR for structural confirmation, to ensure it meets the stringent requirements of our global clientele. A detailed Certificate of Analysis (COA) is provided with each shipment, and we support compliance with relevant regulatory frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound may be moisture-sensitive; ensure containers are sealed after use to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.