Description

2-Pyridinecarboxylic Acid,5-(Trifluoromethyl)-,Ethyl Ester is a high-value trifluoromethylated pyridine derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its core value lies in the unique combination of the pyridine scaffold and the electron-withdrawing trifluoromethyl group, which is essential for modulating the physicochemical properties of target molecules. This compound is primarily needed by R&D and production teams in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of drugs targeting the central nervous system, anti-infectives, and enzyme inhibitors.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in coordination chemistry and catalysts for cross-coupling and other organic transformations.
• Material Science Research: Employed in the synthesis of functionalized polymers, liquid crystals, and organic electronic materials that require fluorinated heterocyclic components.
• Chemical Biology Probes: Utilized to develop molecular probes and tags for studying biological processes due to the distinctive properties imparted by the fluorine atoms.

Basic Information

Product Name	2-Pyridinecarboxylic Acid,5-(Trifluoromethyl)-,Ethyl Ester
CAS No.	128072-94-6
Molecular Formula	C9H8F3NO2
Molecular Weight	219.16 g/mol
Synonyms	Ethyl 5-(Trifluoromethyl)picolinate; 5-(Trifluoromethyl)picolinic Acid Ethyl Ester; Ethyl 5-Trifluoromethylpyridine-2-carboxylate; 2-Carbethoxy-5-trifluoromethylpyridine; 5-Trifluoromethyl-2-pyridinecarboxylic Acid Ethyl Ester; Picolinic acid, 5-(trifluoromethyl)-, ethyl ester; Ethyl 5-(trifluoromethyl)-2-pyridinecarboxylate
EINECS	Contact for details

Quality Control

Our 2-Pyridinecarboxylic Acid,5-(Trifluoromethyl)-,Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for advanced synthetic applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.