Description

1H-Pyrazole-3-Carboxylic Acid, 4-(4-Fluorophenyl)-, Ethyl Ester is a high-purity fluorinated pyrazole derivative, a critical building block in modern organic synthesis. This compound matters for its role as a versatile intermediate in the development of active pharmaceutical ingredients (APIs) and advanced agrochemicals. It is primarily needed by research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce specific fluorinated heterocyclic motifs into their target molecules.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, particularly in therapeutic areas targeting inflammation, oncology, and central nervous system disorders.
• Agrochemical Research: Serves as a core structure for developing new-generation herbicides, fungicides, and insecticides with enhanced efficacy and selectivity.
• Material Science Precursor: Used in the research and development of advanced organic materials, including liquid crystals and organic light-emitting diodes (OLEDs).
• Chemical Biology Probe: Employed in medicinal chemistry for structure-activity relationship (SAR) studies and as a scaffold for designing enzyme inhibitors.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of client-specific target molecules on a commercial scale.

Basic Information

Product Name	1H-Pyrazole-3-Carboxylic Acid, 4-(4-Fluorophenyl)-, Ethyl Ester
CAS No.	127919-73-7
Molecular Formula	C₁₂H₁₁FN₂O₂
Molecular Weight	234.23 g/mol
Synonyms	Ethyl 4-(4-fluorophenyl)-1H-pyrazole-3-carboxylate; 4-(4-Fluorophenyl)-1H-pyrazole-3-carboxylic acid ethyl ester; 4-(p-Fluorophenyl)-1H-pyrazole-3-carboxylic acid ethyl ester; 1H-Pyrazole-3-carboxylic acid, 4-(4-fluorophenyl)-, ethyl ester; 127919-73-7; Ethyl 4-(4-fluorophenyl)-1H-pyrazole-3-carboxylate
EINECS	Contact for details

Quality Control

Our production of 1H-Pyrazole-3-Carboxylic Acid, 4-(4-Fluorophenyl)-, Ethyl Ester adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and rigorous control of residual solvents and impurities. Certificates of Analysis (COA) detailing all specifications are provided with each shipment to ensure full traceability and compliance with your internal quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.