Description

5-(2-Fluorophenyl)-4-Oxazolecarboxylic Acid Ethyl Ester is a high-purity fluorinated heterocyclic building block of significant interest in advanced organic synthesis. This compound matters as a versatile intermediate for constructing complex molecular architectures, particularly in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce fluorinated oxazole motifs into their target molecules.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, especially in medicinal chemistry programs targeting kinase inhibitors, anti-inflammatory agents, and CNS-active compounds.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides where the fluorinated oxazole core can enhance biological activity and environmental stability.
• Material Science Research: Serves as a precursor for functionalized organic molecules used in the development of organic light-emitting diodes (OLEDs) and other electronic materials.
• Chemical Biology Probes: Employed in the synthesis of fluorinated tags and probes for studying biological mechanisms and enzyme interactions.
• Custom Synthesis & Contract Manufacturing: A critical building block for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	5-(2-Fluorophenyl)-4-Oxazolecarboxylic Acid Ethyl Ester
CAS No.	127919-29-3
Molecular Formula	C12H10FNO3
Molecular Weight	235.21 g/mol
Synonyms	Ethyl 5-(2-fluorophenyl)-1,3-oxazole-4-carboxylate; 4-Oxazolecarboxylic acid, 5-(2-fluorophenyl)-, ethyl ester; 5-(2-Fluorophenyl)-4-oxazolecarboxylic acid ethyl ester; 5-(o-Fluorophenyl)-4-oxazolecarboxylic acid ethyl ester; 2-Fluoro-5-(4-(ethoxycarbonyl)-1,3-oxazol-5-yl)benzene (tautomeric form); Oxazole-4-carboxylic acid ethyl ester, 5-(2-fluorophenyl)- derivative; FPOE
EINECS	Contact for details

Quality Control

Our 5-(2-Fluorophenyl)-4-Oxazolecarboxylic Acid Ethyl Ester is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals, to ensure it meets the high standards required for research and process chemistry. Certificates of Analysis (COA) with full traceability are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound should be kept under an inert atmosphere for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.