Description

3-(2,2-Dimethyl-[1,3]Dioxolan-4-Ylmethoxy)-2-Methyl-Propionic Acid Methyl Ester is a high-purity, specialized chemical intermediate with a protected diol functionality. This compound is valued for its role in the synthesis of complex molecules, offering precise reactivity for constructing chiral centers and ether linkages. It is primarily sought by pharmaceutical and fine chemical research & development teams for applications in advanced drug discovery and process chemistry.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring chiral purity and specific ether side chains.
• Fine Chemical Synthesis: Used in the multi-step synthesis of complex organic molecules for agrochemicals, specialty polymers, and advanced materials.
• Chiral Auxiliary/Reagent: Serves as a precursor or reagent in asymmetric synthesis due to its protected diol group, which can be selectively deprotected.
• Process Chemistry Development: Employed in route scouting and optimization for scalable manufacturing of target molecules in R&D and pilot plants.
• Academic & Industrial Research: Utilized in chemical biology and medicinal chemistry research for probing biological pathways and developing new therapeutic candidates.

Basic Information

Product Name	3-(2,2-Dimethyl-[1,3]Dioxolan-4-Ylmethoxy)-2-Methyl-Propionic Acid Methyl Ester
CAS No.	127902-51-6
Molecular Formula	C12H22O5
Molecular Weight	246.30 g/mol
Synonyms	Methyl 3-[(2,2-dimethyl-1,3-dioxolan-4-yl)methoxy]-2-methylpropanoate; 2-Methyl-3-[(2,2-dimethyl-1,3-dioxolan-4-yl)methoxy]propionic acid methyl ester; 3-[(2,2-Dimethyl-1,3-dioxolan-4-yl)methoxy]-2-methylpropanoic acid methyl ester; Acetonide-protected glycerol ether methyl ester; (4-Methoxymethyl-2,2-dimethyl-1,3-dioxolan-4-yl)methyl 2-methylpropionate (related structure).
EINECS	Contact for details

Quality Control

Our production of 3-(2,2-Dimethyl-[1,3]Dioxolan-4-Ylmethoxy)-2-Methyl-Propionic Acid Methyl Ester adheres to stringent quality protocols. Each batch is characterized and tested to ensure identity, purity, and consistency, meeting the exacting standards required for pharmaceutical R&D. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are available upon request to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage under inert atmosphere, please contact us for specific recommendations.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Purity (GC)	≥ 98.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.