Description

Bis(Trimethylsilyl)-n-tert-Butylacetaldimine is a specialized organosilicon reagent featuring a protected imine functional group. This compound is valued for its role as a versatile building block in organic synthesis, particularly for introducing the tert-butylacetaldimine moiety under mild conditions. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and advanced materials sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for compounds requiring chiral amine or amino acid derivatives.
• Asymmetric Synthesis: Used as a chiral auxiliary or reagent in stereoselective reactions to create enantiomerically pure compounds.
• Ligand Synthesis: Employed in the preparation of nitrogen-containing ligands for catalysis and coordination chemistry.
• Polymer Modification: Acts as a functionalizing agent to introduce imine or amine groups into polymer backbones for specialty materials.
• Agrochemical Research: Utilized in the development of novel herbicides, fungicides, and insecticides that contain nitrogen heterocycles.
• Academic & Industrial R&D: A valuable tool for methodological development and exploring new reaction pathways in organic chemistry laboratories.

Basic Information

Product Name	Bis(Trimethylsilyl)-n-tert-Butylacetaldimine
CAS No.	127896-07-5
Molecular Formula	C12H29NSi2
Molecular Weight	243.54 g/mol
Synonyms	N-(tert-Butyl)-1,1-bis(trimethylsilyl)ethanimine; 1,1-Bis(trimethylsilyl)-N-tert-butylacetaldimine; N-tert-Butyl-1,1-bis(trimethylsilyl)ethanimine; (E)-N-(tert-Butyl)-1,1-bis(trimethylsilyl)ethan-1-imine; BSA-t-Bu; Bis(trimethylsilyl)acetaldehyde tert-butylimine; tert-Butyl 1,1-bis(trimethylsilyl)ethylideneamine
EINECS	Contact for details

Quality Control

Our Bis(Trimethylsilyl)-n-tert-Butylacetaldimine is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including NMR, GC, and HPLC, to ensure high chemical purity and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and absence of critical impurities. We support cGMP manufacturing standards for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (argon or nitrogen) to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Purity (HPLC)	≥ 96.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.