Description

Butanoic Acid, 4-[[(1,1-Dimethylethoxy)Carbonyl]Amino]-3-Hydroxy-, (S)- (9Ci) is a chiral, N-Boc-protected amino acid derivative of significant interest in advanced organic synthesis. This compound matters as a high-purity, stereochemically defined building block, enabling the precise construction of complex molecules with defined three-dimensional architecture. It is primarily needed by pharmaceutical R&D and fine chemical manufacturers for applications in peptide synthesis and the development of novel active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel therapeutic peptides and small molecule drugs.
• Peptide Synthesis: Used as a protected amino acid building block in solid-phase and solution-phase peptide synthesis (SPPS).
• Protease Inhibitor Development: Serves as a core structural component in the design and synthesis of enzyme inhibitors targeting proteases.
• Chemical Biology Research: Employed in the synthesis of labeled compounds, probes, and modified peptides for biochemical and cellular studies.
• Asymmetric Synthesis: Utilized in catalytic asymmetric reactions to introduce chiral centers into more complex molecular frameworks.
• Fine Chemical Production: Acts as a precursor in the multi-step synthesis of specialized, high-value fine chemicals and catalysts.

Basic Information

Product Name	Butanoic Acid, 4-[[(1,1-Dimethylethoxy)Carbonyl]Amino]-3-Hydroxy-, (S)- (9Ci)
CAS No.	127852-78-2
Molecular Formula	C10H19NO5
Molecular Weight	233.26 g/mol
Synonyms	(S)-4-[(tert-Butoxycarbonyl)amino]-3-hydroxybutanoic acid; (S)-3-Hydroxy-4-[(tert-butoxycarbonyl)amino]butyric acid; Boc-HOBut-OH; Boc-3-hydroxy-D-homoalanine; N-Boc-L-3-Hydroxyhomoserine; 4-[(tert-Butoxycarbonyl)amino]-3-hydroxybutanoic acid; (S)-4-(Boc-amino)-3-hydroxybutyric acid; N-Boc-3-hydroxy-L-homoserine
EINECS	Contact for details

Quality Control

Our Butanoic Acid, 4-[[(1,1-Dimethylethoxy)Carbonyl]Amino]-3-Hydroxy-, (S)- (9Ci) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with exacting standards for pharmaceutical intermediates. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions; consider storage under an inert atmosphere for long-term preservation of quality.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.